Stimulation of motilin secretion by bile, free fatty acids, and acidification in human duodenal organoids

Objective: Motilin is a proximal small intestinal hormone with roles in gastrointestinal motility, gallbladder emptying, and hunger initiation. In vivo motilin release is stimulated by fats, bile, and duodenal acidification but the underlying molecular mechanisms of motilin secretion remain poorly u...

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Autores principales: Emily L. Miedzybrodzka, Rachel E. Foreman, Van B. Lu, Amy L. George, Christopher A. Smith, Pierre Larraufie, Richard G. Kay, Deborah A. Goldspink, Frank Reimann, Fiona M. Gribble
Formato: article
Lenguaje:EN
Publicado: Elsevier 2021
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Acceso en línea:https://doaj.org/article/7038fb1fad7e44e6bafe941133cf6234
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