Expression of CD20 after viral reactivation renders HIV-reservoir cells susceptible to Rituximab

Here, the authors identify B lymphocyte antigen CD20 as a marker for HIV-infected T cells and provide evidence for the potential use of anti-CD20 antibodies in combination with latency reversing agents for depletion of viral reactivated CD4 T cells in patients on antiretroviral therapy.

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Autores principales:	Carla Serra-Peinado, Judith Grau-Expósito, Laura Luque-Ballesteros, Antonio Astorga-Gamaza, Jordi Navarro, Jenny Gallego-Rodriguez, Mario Martin, Adrià Curran, Joaquin Burgos, Esteban Ribera, Berta Raventós, Rein Willekens, Ariadna Torrella, Bibiana Planas, Rosa Badía, Felipe Garcia, Josep Castellví, Meritxell Genescà, Vicenç Falcó, Maria J. Buzon
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/704040ec0d7d48cf90855591b8bb7358
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spelling	oai:doaj.org-article:704040ec0d7d48cf90855591b8bb73582021-12-02T15:35:10ZExpression of CD20 after viral reactivation renders HIV-reservoir cells susceptible to Rituximab10.1038/s41467-019-11556-42041-1723https://doaj.org/article/704040ec0d7d48cf90855591b8bb73582019-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11556-4https://doaj.org/toc/2041-1723Here, the authors identify B lymphocyte antigen CD20 as a marker for HIV-infected T cells and provide evidence for the potential use of anti-CD20 antibodies in combination with latency reversing agents for depletion of viral reactivated CD4 T cells in patients on antiretroviral therapy.Carla Serra-PeinadoJudith Grau-ExpósitoLaura Luque-BallesterosAntonio Astorga-GamazaJordi NavarroJenny Gallego-RodriguezMario MartinAdrià CurranJoaquin BurgosEsteban RiberaBerta RaventósRein WillekensAriadna TorrellaBibiana PlanasRosa BadíaFelipe GarciaJosep CastellvíMeritxell GenescàVicenç FalcóMaria J. BuzonNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Carla Serra-Peinado Judith Grau-Expósito Laura Luque-Ballesteros Antonio Astorga-Gamaza Jordi Navarro Jenny Gallego-Rodriguez Mario Martin Adrià Curran Joaquin Burgos Esteban Ribera Berta Raventós Rein Willekens Ariadna Torrella Bibiana Planas Rosa Badía Felipe Garcia Josep Castellví Meritxell Genescà Vicenç Falcó Maria J. Buzon Expression of CD20 after viral reactivation renders HIV-reservoir cells susceptible to Rituximab
description	Here, the authors identify B lymphocyte antigen CD20 as a marker for HIV-infected T cells and provide evidence for the potential use of anti-CD20 antibodies in combination with latency reversing agents for depletion of viral reactivated CD4 T cells in patients on antiretroviral therapy.
format	article
author	Carla Serra-Peinado Judith Grau-Expósito Laura Luque-Ballesteros Antonio Astorga-Gamaza Jordi Navarro Jenny Gallego-Rodriguez Mario Martin Adrià Curran Joaquin Burgos Esteban Ribera Berta Raventós Rein Willekens Ariadna Torrella Bibiana Planas Rosa Badía Felipe Garcia Josep Castellví Meritxell Genescà Vicenç Falcó Maria J. Buzon
author_facet	Carla Serra-Peinado Judith Grau-Expósito Laura Luque-Ballesteros Antonio Astorga-Gamaza Jordi Navarro Jenny Gallego-Rodriguez Mario Martin Adrià Curran Joaquin Burgos Esteban Ribera Berta Raventós Rein Willekens Ariadna Torrella Bibiana Planas Rosa Badía Felipe Garcia Josep Castellví Meritxell Genescà Vicenç Falcó Maria J. Buzon
author_sort	Carla Serra-Peinado
title	Expression of CD20 after viral reactivation renders HIV-reservoir cells susceptible to Rituximab
title_short	Expression of CD20 after viral reactivation renders HIV-reservoir cells susceptible to Rituximab
title_full	Expression of CD20 after viral reactivation renders HIV-reservoir cells susceptible to Rituximab
title_fullStr	Expression of CD20 after viral reactivation renders HIV-reservoir cells susceptible to Rituximab
title_full_unstemmed	Expression of CD20 after viral reactivation renders HIV-reservoir cells susceptible to Rituximab
title_sort	expression of cd20 after viral reactivation renders hiv-reservoir cells susceptible to rituximab
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/704040ec0d7d48cf90855591b8bb7358
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Expression of CD20 after viral reactivation renders HIV-reservoir cells susceptible to Rituximab

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