Frequency of Diabetic Ketoacidosis and Severe Hypoglycemia in Children with Type 1 Diabetes

Background and Objective: Diabetic ketoacidosis and severe hypoglycemia are common and recurrent acute complications of type 1 diabetes and are associated with high mortality and morbidity. The aim of this study was to determine the frequency of diabetic ketoacidosis and hypoglycemia in children wit...

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Autores principales: A Homaei, F Saffari, E Parsarad, ZS Mohammadi
Formato: article
Lenguaje:EN
FA
Publicado: Babol University of Medical Sciences 2022
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Acceso en línea:https://doaj.org/article/7044cd696ba243fcb2bb5518f44d5ab1
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spelling oai:doaj.org-article:7044cd696ba243fcb2bb5518f44d5ab12021-12-05T07:16:35ZFrequency of Diabetic Ketoacidosis and Severe Hypoglycemia in Children with Type 1 Diabetes1561-41072251-7170https://doaj.org/article/7044cd696ba243fcb2bb5518f44d5ab12022-03-01T00:00:00Zhttp://jbums.org/article-1-9637-en.htmlhttps://doaj.org/toc/1561-4107https://doaj.org/toc/2251-7170Background and Objective: Diabetic ketoacidosis and severe hypoglycemia are common and recurrent acute complications of type 1 diabetes and are associated with high mortality and morbidity. The aim of this study was to determine the frequency of diabetic ketoacidosis and hypoglycemia in children with type 1 diabetes. Methods: In this retrospective cross-sectional study, 480 patients with type 1 diabetes admitted to the Children Hospital in Qazvin were enrolled by census method. Demographic characteristics, season of referral, place of residence, existence of type 1 diabetes in the family, kin relationship of parents, cause of hospitalization (hyperglycemia, hypoglycemia and diabetic ketoacidosis) and length of hospital stay were extracted from the files and examined. Findings: Most patients (62.9%) were female. 46%, 44.4% and 9.6% of patients were admitted with diabetic ketoacidosis, hyperglycemia and hypoglycemia, respectively. 47.96% of patients had severe diabetic ketoacidosis. 49.3% of patients had ketoacidosis with infection and 20% of known cases were hospitalized due to poor insulin compliance. Hospitalization days were significantly higher in patients with ketoacidosis (p=0.00). Conclusion: According to the results of this study, the occurrence of infection and lack of adherence to insulin use were the main cause of hospitalization in patients with diabetes, which led to an increase in hospitalization days in these patients. Adequate training to regulate blood sugar reduces the rate of hospitalizations.A HomaeiF SaffariE ParsaradZS MohammadiBabol University of Medical Sciencesarticletype 1 diabetes mellitusdiabetic ketoacidosishypoglycemiainsulinhyperglycemia.MedicineRMedicine (General)R5-920ENFAMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, Vol 24, Iss 1, Pp 1-9 (2022)
institution DOAJ
collection DOAJ
language EN
FA
topic type 1 diabetes mellitus
diabetic ketoacidosis
hypoglycemia
insulin
hyperglycemia.
Medicine
R
Medicine (General)
R5-920
spellingShingle type 1 diabetes mellitus
diabetic ketoacidosis
hypoglycemia
insulin
hyperglycemia.
Medicine
R
Medicine (General)
R5-920
A Homaei
F Saffari
E Parsarad
ZS Mohammadi
Frequency of Diabetic Ketoacidosis and Severe Hypoglycemia in Children with Type 1 Diabetes
description Background and Objective: Diabetic ketoacidosis and severe hypoglycemia are common and recurrent acute complications of type 1 diabetes and are associated with high mortality and morbidity. The aim of this study was to determine the frequency of diabetic ketoacidosis and hypoglycemia in children with type 1 diabetes. Methods: In this retrospective cross-sectional study, 480 patients with type 1 diabetes admitted to the Children Hospital in Qazvin were enrolled by census method. Demographic characteristics, season of referral, place of residence, existence of type 1 diabetes in the family, kin relationship of parents, cause of hospitalization (hyperglycemia, hypoglycemia and diabetic ketoacidosis) and length of hospital stay were extracted from the files and examined. Findings: Most patients (62.9%) were female. 46%, 44.4% and 9.6% of patients were admitted with diabetic ketoacidosis, hyperglycemia and hypoglycemia, respectively. 47.96% of patients had severe diabetic ketoacidosis. 49.3% of patients had ketoacidosis with infection and 20% of known cases were hospitalized due to poor insulin compliance. Hospitalization days were significantly higher in patients with ketoacidosis (p=0.00). Conclusion: According to the results of this study, the occurrence of infection and lack of adherence to insulin use were the main cause of hospitalization in patients with diabetes, which led to an increase in hospitalization days in these patients. Adequate training to regulate blood sugar reduces the rate of hospitalizations.
format article
author A Homaei
F Saffari
E Parsarad
ZS Mohammadi
author_facet A Homaei
F Saffari
E Parsarad
ZS Mohammadi
author_sort A Homaei
title Frequency of Diabetic Ketoacidosis and Severe Hypoglycemia in Children with Type 1 Diabetes
title_short Frequency of Diabetic Ketoacidosis and Severe Hypoglycemia in Children with Type 1 Diabetes
title_full Frequency of Diabetic Ketoacidosis and Severe Hypoglycemia in Children with Type 1 Diabetes
title_fullStr Frequency of Diabetic Ketoacidosis and Severe Hypoglycemia in Children with Type 1 Diabetes
title_full_unstemmed Frequency of Diabetic Ketoacidosis and Severe Hypoglycemia in Children with Type 1 Diabetes
title_sort frequency of diabetic ketoacidosis and severe hypoglycemia in children with type 1 diabetes
publisher Babol University of Medical Sciences
publishDate 2022
url https://doaj.org/article/7044cd696ba243fcb2bb5518f44d5ab1
work_keys_str_mv AT ahomaei frequencyofdiabeticketoacidosisandseverehypoglycemiainchildrenwithtype1diabetes
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AT zsmohammadi frequencyofdiabeticketoacidosisandseverehypoglycemiainchildrenwithtype1diabetes
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