Optimisation of a PC12 cell-based in vitro stroke model for screening neuroprotective agents
Abstract Stroke causes death and disability globally but no neuroprotectant is approved for post-stroke neuronal injury. Neuroprotective compounds can be identified using oxygen glucose deprivation (OGD) of neuronal cells as an in vitro stroke model. Nerve growth factor (NGF)-differentiated PC12 phe...
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Autores principales: | PinFen Chua, William K. Lim |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/704ee4132a274bdaa404810324e826c4 |
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