Optimisation of a PC12 cell-based in vitro stroke model for screening neuroprotective agents

Abstract Stroke causes death and disability globally but no neuroprotectant is approved for post-stroke neuronal injury. Neuroprotective compounds can be identified using oxygen glucose deprivation (OGD) of neuronal cells as an in vitro stroke model. Nerve growth factor (NGF)-differentiated PC12 phe...

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Autores principales: PinFen Chua, William K. Lim
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/704ee4132a274bdaa404810324e826c4
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