Concerted dynamics of metallo-base pairs in an A/B-form helical transition

Metal-mediated base pairs expand the repertoire of nucleic acid structures and dynamics. Here, the authors prepared a metallo-DNA duplex including two C-Hg(II)-T base pairs separated by six normal Watson-Crick base pairs and investigated its solution structure and dynamics using NMR spectroscopy.

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Autores principales:	Olivia P. Schmidt, Simon Jurt, Silke Johannsen, Ashkan Karimi, Roland K. O. Sigel, Nathan W. Luedtke
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/705350ae06484a6f9608fbfdda995bdc
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spelling	oai:doaj.org-article:705350ae06484a6f9608fbfdda995bdc2021-12-02T16:58:16ZConcerted dynamics of metallo-base pairs in an A/B-form helical transition10.1038/s41467-019-12440-x2041-1723https://doaj.org/article/705350ae06484a6f9608fbfdda995bdc2019-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12440-xhttps://doaj.org/toc/2041-1723Metal-mediated base pairs expand the repertoire of nucleic acid structures and dynamics. Here, the authors prepared a metallo-DNA duplex including two C-Hg(II)-T base pairs separated by six normal Watson-Crick base pairs and investigated its solution structure and dynamics using NMR spectroscopy.Olivia P. SchmidtSimon JurtSilke JohannsenAshkan KarimiRoland K. O. SigelNathan W. LuedtkeNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Olivia P. Schmidt Simon Jurt Silke Johannsen Ashkan Karimi Roland K. O. Sigel Nathan W. Luedtke Concerted dynamics of metallo-base pairs in an A/B-form helical transition
description	Metal-mediated base pairs expand the repertoire of nucleic acid structures and dynamics. Here, the authors prepared a metallo-DNA duplex including two C-Hg(II)-T base pairs separated by six normal Watson-Crick base pairs and investigated its solution structure and dynamics using NMR spectroscopy.
format	article
author	Olivia P. Schmidt Simon Jurt Silke Johannsen Ashkan Karimi Roland K. O. Sigel Nathan W. Luedtke
author_facet	Olivia P. Schmidt Simon Jurt Silke Johannsen Ashkan Karimi Roland K. O. Sigel Nathan W. Luedtke
author_sort	Olivia P. Schmidt
title	Concerted dynamics of metallo-base pairs in an A/B-form helical transition
title_short	Concerted dynamics of metallo-base pairs in an A/B-form helical transition
title_full	Concerted dynamics of metallo-base pairs in an A/B-form helical transition
title_fullStr	Concerted dynamics of metallo-base pairs in an A/B-form helical transition
title_full_unstemmed	Concerted dynamics of metallo-base pairs in an A/B-form helical transition
title_sort	concerted dynamics of metallo-base pairs in an a/b-form helical transition
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/705350ae06484a6f9608fbfdda995bdc
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Concerted dynamics of metallo-base pairs in an A/B-form helical transition

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