Concerted dynamics of metallo-base pairs in an A/B-form helical transition
Metal-mediated base pairs expand the repertoire of nucleic acid structures and dynamics. Here, the authors prepared a metallo-DNA duplex including two C-Hg(II)-T base pairs separated by six normal Watson-Crick base pairs and investigated its solution structure and dynamics using NMR spectroscopy.
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Main Authors: | Olivia P. Schmidt, Simon Jurt, Silke Johannsen, Ashkan Karimi, Roland K. O. Sigel, Nathan W. Luedtke |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2019
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Subjects: | |
Online Access: | https://doaj.org/article/705350ae06484a6f9608fbfdda995bdc |
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