Concerted dynamics of metallo-base pairs in an A/B-form helical transition

Metal-mediated base pairs expand the repertoire of nucleic acid structures and dynamics. Here, the authors prepared a metallo-DNA duplex including two C-Hg(II)-T base pairs separated by six normal Watson-Crick base pairs and investigated its solution structure and dynamics using NMR spectroscopy.

Saved in:
Bibliographic Details
Main Authors: Olivia P. Schmidt, Simon Jurt, Silke Johannsen, Ashkan Karimi, Roland K. O. Sigel, Nathan W. Luedtke
Format: article
Language:EN
Published: Nature Portfolio 2019
Subjects:
Q
Online Access:https://doaj.org/article/705350ae06484a6f9608fbfdda995bdc
Tags: Add Tag
No Tags, Be the first to tag this record!