Immunity-mediated diseases and human immunogenetics (accomplishments and prospects)

Type 1 diabetes mellitus (T1DM) was used from the viewpoint of human immunogenetics as an example of the most widely studied immunity-mediated disease. This was done in order to develop, approve and implement a new clinical approach to determine immunity-mediated susceptibility or resistance to auto...

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Autores principales:	Ivan Ivanovich Dedov, Rakhim Musaevich Khaitov, Leonid Petrovich Alexeev
Formato:	article
Lenguaje:	EN RU
Publicado:	Endocrinology Research Centre 2016
Materias:	type 1 diabetes mellitus immunogenetics immunity-mediated diseases Nutritional diseases. Deficiency diseases RC620-627
Acceso en línea:	https://doaj.org/article/705508fe96a2421c890aeda42561fbbe
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spelling	oai:doaj.org-article:705508fe96a2421c890aeda42561fbbe2021-11-14T09:00:20ZImmunity-mediated diseases and human immunogenetics (accomplishments and prospects)2072-03512072-037810.14341/DM7775https://doaj.org/article/705508fe96a2421c890aeda42561fbbe2016-01-01T00:00:00Zhttps://www.dia-endojournals.ru/jour/article/view/7775https://doaj.org/toc/2072-0351https://doaj.org/toc/2072-0378Type 1 diabetes mellitus (T1DM) was used from the viewpoint of human immunogenetics as an example of the most widely studied immunity-mediated disease. This was done in order to develop, approve and implement a new clinical approach to determine immunity-mediated susceptibility or resistance to autoimmune diseases. The approach is based on analysis of entire HLA-DRB1 genotypes (not separate HLA-DRB1 haplotypes) of the study participants. Therefore, more effective and personalised classification of T1DM risk groups was achieved by exclusion from significant contingents.Ivan Ivanovich DedovRakhim Musaevich KhaitovLeonid Petrovich AlexeevEndocrinology Research Centrearticletype 1 diabetes mellitusimmunogeneticsimmunity-mediated diseasesNutritional diseases. Deficiency diseasesRC620-627ENRUСахарный диабет, Vol 19, Iss 1, Pp 8-15 (2016)
institution	DOAJ
collection	DOAJ
language	EN RU
topic	type 1 diabetes mellitus immunogenetics immunity-mediated diseases Nutritional diseases. Deficiency diseases RC620-627
spellingShingle	type 1 diabetes mellitus immunogenetics immunity-mediated diseases Nutritional diseases. Deficiency diseases RC620-627 Ivan Ivanovich Dedov Rakhim Musaevich Khaitov Leonid Petrovich Alexeev Immunity-mediated diseases and human immunogenetics (accomplishments and prospects)
description	Type 1 diabetes mellitus (T1DM) was used from the viewpoint of human immunogenetics as an example of the most widely studied immunity-mediated disease. This was done in order to develop, approve and implement a new clinical approach to determine immunity-mediated susceptibility or resistance to autoimmune diseases. The approach is based on analysis of entire HLA-DRB1 genotypes (not separate HLA-DRB1 haplotypes) of the study participants. Therefore, more effective and personalised classification of T1DM risk groups was achieved by exclusion from significant contingents.
format	article
author	Ivan Ivanovich Dedov Rakhim Musaevich Khaitov Leonid Petrovich Alexeev
author_facet	Ivan Ivanovich Dedov Rakhim Musaevich Khaitov Leonid Petrovich Alexeev
author_sort	Ivan Ivanovich Dedov
title	Immunity-mediated diseases and human immunogenetics (accomplishments and prospects)
title_short	Immunity-mediated diseases and human immunogenetics (accomplishments and prospects)
title_full	Immunity-mediated diseases and human immunogenetics (accomplishments and prospects)
title_fullStr	Immunity-mediated diseases and human immunogenetics (accomplishments and prospects)
title_full_unstemmed	Immunity-mediated diseases and human immunogenetics (accomplishments and prospects)
title_sort	immunity-mediated diseases and human immunogenetics (accomplishments and prospects)
publisher	Endocrinology Research Centre
publishDate	2016
url	https://doaj.org/article/705508fe96a2421c890aeda42561fbbe
work_keys_str_mv	AT ivanivanovichdedov immunitymediateddiseasesandhumanimmunogeneticsaccomplishmentsandprospects AT rakhimmusaevichkhaitov immunitymediateddiseasesandhumanimmunogeneticsaccomplishmentsandprospects AT leonidpetrovichalexeev immunitymediateddiseasesandhumanimmunogeneticsaccomplishmentsandprospects
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Immunity-mediated diseases and human immunogenetics (accomplishments and prospects)

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