Native characterization of nucleic acid motif thermodynamics via non-covalent catalysis
DNA hybridisation thermodynamics parameters underlie rational design of oligonucleotides for diagnostics and nanotechnology. Here, the authors present an accurate method to measure the free energy of a given DNA structure at specific temperature and buffer conditions.
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Nature Portfolio
2016
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oai:doaj.org-article:70563125abd9404bb53282d9b53de0f42021-12-02T16:49:57ZNative characterization of nucleic acid motif thermodynamics via non-covalent catalysis10.1038/ncomms103192041-1723https://doaj.org/article/70563125abd9404bb53282d9b53de0f42016-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms10319https://doaj.org/toc/2041-1723DNA hybridisation thermodynamics parameters underlie rational design of oligonucleotides for diagnostics and nanotechnology. Here, the authors present an accurate method to measure the free energy of a given DNA structure at specific temperature and buffer conditions.Chunyan WangJin H. BaeDavid Yu ZhangNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-11 (2016) |
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Science Q Chunyan Wang Jin H. Bae David Yu Zhang Native characterization of nucleic acid motif thermodynamics via non-covalent catalysis |
description |
DNA hybridisation thermodynamics parameters underlie rational design of oligonucleotides for diagnostics and nanotechnology. Here, the authors present an accurate method to measure the free energy of a given DNA structure at specific temperature and buffer conditions. |
format |
article |
author |
Chunyan Wang Jin H. Bae David Yu Zhang |
author_facet |
Chunyan Wang Jin H. Bae David Yu Zhang |
author_sort |
Chunyan Wang |
title |
Native characterization of nucleic acid motif thermodynamics via non-covalent catalysis |
title_short |
Native characterization of nucleic acid motif thermodynamics via non-covalent catalysis |
title_full |
Native characterization of nucleic acid motif thermodynamics via non-covalent catalysis |
title_fullStr |
Native characterization of nucleic acid motif thermodynamics via non-covalent catalysis |
title_full_unstemmed |
Native characterization of nucleic acid motif thermodynamics via non-covalent catalysis |
title_sort |
native characterization of nucleic acid motif thermodynamics via non-covalent catalysis |
publisher |
Nature Portfolio |
publishDate |
2016 |
url |
https://doaj.org/article/70563125abd9404bb53282d9b53de0f4 |
work_keys_str_mv |
AT chunyanwang nativecharacterizationofnucleicacidmotifthermodynamicsvianoncovalentcatalysis AT jinhbae nativecharacterizationofnucleicacidmotifthermodynamicsvianoncovalentcatalysis AT davidyuzhang nativecharacterizationofnucleicacidmotifthermodynamicsvianoncovalentcatalysis |
_version_ |
1718383164131377152 |