Native characterization of nucleic acid motif thermodynamics via non-covalent catalysis

DNA hybridisation thermodynamics parameters underlie rational design of oligonucleotides for diagnostics and nanotechnology. Here, the authors present an accurate method to measure the free energy of a given DNA structure at specific temperature and buffer conditions.

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Autores principales: Chunyan Wang, Jin H. Bae, David Yu Zhang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/70563125abd9404bb53282d9b53de0f4
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spelling oai:doaj.org-article:70563125abd9404bb53282d9b53de0f42021-12-02T16:49:57ZNative characterization of nucleic acid motif thermodynamics via non-covalent catalysis10.1038/ncomms103192041-1723https://doaj.org/article/70563125abd9404bb53282d9b53de0f42016-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms10319https://doaj.org/toc/2041-1723DNA hybridisation thermodynamics parameters underlie rational design of oligonucleotides for diagnostics and nanotechnology. Here, the authors present an accurate method to measure the free energy of a given DNA structure at specific temperature and buffer conditions.Chunyan WangJin H. BaeDavid Yu ZhangNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Chunyan Wang
Jin H. Bae
David Yu Zhang
Native characterization of nucleic acid motif thermodynamics via non-covalent catalysis
description DNA hybridisation thermodynamics parameters underlie rational design of oligonucleotides for diagnostics and nanotechnology. Here, the authors present an accurate method to measure the free energy of a given DNA structure at specific temperature and buffer conditions.
format article
author Chunyan Wang
Jin H. Bae
David Yu Zhang
author_facet Chunyan Wang
Jin H. Bae
David Yu Zhang
author_sort Chunyan Wang
title Native characterization of nucleic acid motif thermodynamics via non-covalent catalysis
title_short Native characterization of nucleic acid motif thermodynamics via non-covalent catalysis
title_full Native characterization of nucleic acid motif thermodynamics via non-covalent catalysis
title_fullStr Native characterization of nucleic acid motif thermodynamics via non-covalent catalysis
title_full_unstemmed Native characterization of nucleic acid motif thermodynamics via non-covalent catalysis
title_sort native characterization of nucleic acid motif thermodynamics via non-covalent catalysis
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/70563125abd9404bb53282d9b53de0f4
work_keys_str_mv AT chunyanwang nativecharacterizationofnucleicacidmotifthermodynamicsvianoncovalentcatalysis
AT jinhbae nativecharacterizationofnucleicacidmotifthermodynamicsvianoncovalentcatalysis
AT davidyuzhang nativecharacterizationofnucleicacidmotifthermodynamicsvianoncovalentcatalysis
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