Transgenic Tmc2 expression preserves inner ear hair cells and vestibular function in mice lacking Tmc1

Abstract Recent work has demonstrated that transmembrane channel-like 1 protein (TMC1) is an essential component of the sensory transduction complex in hair cells of the inner ear. A closely related homolog, TMC2, is expressed transiently in the neonatal mouse cochlea and can enable sensory transduc...

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Main Authors: Yukako Asai, Bifeng Pan, Carl Nist-Lund, Alice Galvin, Andrei N. Lukashkin, Victoria A. Lukashkina, Tianwen Chen, Wu Zhou, Hong Zhu, Ian J. Russell, Jeffrey R. Holt, Gwenaelle S. G. Géléoc
Format: article
Language:EN
Published: Nature Portfolio 2018
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Online Access:https://doaj.org/article/7060bb4179c3426d8a8e22cd46477d42
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