PDZD8 interacts with Protrudin and Rab7 at ER-late endosome membrane contact sites associated with mitochondria

Membrane contact sites between organelles have been shown to play important biological roles. Here, the authors show that at the ER, PDZD8 associates with Protrudin and also with Rab7 endosomes and recruits mitochondria to form three-way contacts.

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Autores principales:	Yael Elbaz-Alon, Yuting Guo, Nadav Segev, Michal Harel, Daniel E. Quinnell, Tamar Geiger, Ori Avinoam, Dong Li, Jodi Nunnari
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/707039eaf48b40168be3bf1f7653eaa0
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spelling	oai:doaj.org-article:707039eaf48b40168be3bf1f7653eaa02021-12-02T17:55:14ZPDZD8 interacts with Protrudin and Rab7 at ER-late endosome membrane contact sites associated with mitochondria10.1038/s41467-020-17451-72041-1723https://doaj.org/article/707039eaf48b40168be3bf1f7653eaa02020-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17451-7https://doaj.org/toc/2041-1723Membrane contact sites between organelles have been shown to play important biological roles. Here, the authors show that at the ER, PDZD8 associates with Protrudin and also with Rab7 endosomes and recruits mitochondria to form three-way contacts.Yael Elbaz-AlonYuting GuoNadav SegevMichal HarelDaniel E. QuinnellTamar GeigerOri AvinoamDong LiJodi NunnariNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Yael Elbaz-Alon Yuting Guo Nadav Segev Michal Harel Daniel E. Quinnell Tamar Geiger Ori Avinoam Dong Li Jodi Nunnari PDZD8 interacts with Protrudin and Rab7 at ER-late endosome membrane contact sites associated with mitochondria
description	Membrane contact sites between organelles have been shown to play important biological roles. Here, the authors show that at the ER, PDZD8 associates with Protrudin and also with Rab7 endosomes and recruits mitochondria to form three-way contacts.
format	article
author	Yael Elbaz-Alon Yuting Guo Nadav Segev Michal Harel Daniel E. Quinnell Tamar Geiger Ori Avinoam Dong Li Jodi Nunnari
author_facet	Yael Elbaz-Alon Yuting Guo Nadav Segev Michal Harel Daniel E. Quinnell Tamar Geiger Ori Avinoam Dong Li Jodi Nunnari
author_sort	Yael Elbaz-Alon
title	PDZD8 interacts with Protrudin and Rab7 at ER-late endosome membrane contact sites associated with mitochondria
title_short	PDZD8 interacts with Protrudin and Rab7 at ER-late endosome membrane contact sites associated with mitochondria
title_full	PDZD8 interacts with Protrudin and Rab7 at ER-late endosome membrane contact sites associated with mitochondria
title_fullStr	PDZD8 interacts with Protrudin and Rab7 at ER-late endosome membrane contact sites associated with mitochondria
title_full_unstemmed	PDZD8 interacts with Protrudin and Rab7 at ER-late endosome membrane contact sites associated with mitochondria
title_sort	pdzd8 interacts with protrudin and rab7 at er-late endosome membrane contact sites associated with mitochondria
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/707039eaf48b40168be3bf1f7653eaa0
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PDZD8 interacts with Protrudin and Rab7 at ER-late endosome membrane contact sites associated with mitochondria

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