Less is more: Biased loss of CpG dinucleotides strengthens antiviral immunity.
Viruses may not only affect our daily lives but also shape our genome evolution. A recent study shows that the zinc-finger antiviral protein (ZAP) drives CpG suppression in a biased manner. Genes involved in the defense against viral invaders are particularly CpG suppressed to avoid self-targeting a...
Guardado en:
Autores principales: | Daniel Sauter, Frank Kirchhoff |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/7076294ccbf04b95b0f2fe6213b5c9da |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Parvovirus b19 DNA CpG dinucleotide methylation and epigenetic regulation of viral expression.
por: Francesca Bonvicini, et al.
Publicado: (2012) -
The CpG dinucleotide content of the HIV-1 envelope gene may predict disease progression
por: Mishi Kaushal Wasson, et al.
Publicado: (2017) -
SARS-CoV-2 Is Restricted by Zinc Finger Antiviral Protein despite Preadaptation to the Low-CpG Environment in Humans
por: Rayhane Nchioua, et al.
Publicado: (2020) -
Uracil Accumulation and Mutagenesis Dominated by Cytosine Deamination in CpG Dinucleotides in Mice Lacking UNG and SMUG1
por: Lene Alsøe, et al.
Publicado: (2017) -
Low biological fluctuation of mitochondrial CpG and non-CpG methylation at the single-molecule level
por: Chloe Goldsmith, et al.
Publicado: (2021)