Less is more: Biased loss of CpG dinucleotides strengthens antiviral immunity.

Viruses may not only affect our daily lives but also shape our genome evolution. A recent study shows that the zinc-finger antiviral protein (ZAP) drives CpG suppression in a biased manner. Genes involved in the defense against viral invaders are particularly CpG suppressed to avoid self-targeting a...

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Bibliographic Details
Main Authors: Daniel Sauter, Frank Kirchhoff
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2021
Subjects:
Online Access:https://doaj.org/article/7076294ccbf04b95b0f2fe6213b5c9da
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