The inflammatory kinase MAP4K4 promotes reactivation of Kaposi's sarcoma herpesvirus and enhances the invasiveness of infected endothelial cells.

The inflammatory kinase MAP4K4 promotes reactivation of Kaposi's sarcoma herpesvirus and enhances the invasiveness of infected endothelial cells.

Kaposi's sarcoma (KS) is a mesenchymal tumour, which is caused by Kaposi's sarcoma herpesvirus (KSHV) and develops under inflammatory conditions. KSHV-infected endothelial spindle cells, the neoplastic cells in KS, show increased invasiveness, attributed to the elevated expression of metal...

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Détails bibliographiques
Auteurs principaux: Darya A Haas, Kiran Bala, Guntram Büsche, Magdalena Weidner-Glunde, Susann Santag, Semra Kati, Silvia Gramolelli, Modester Damas, Oliver Dittrich-Breiholz, Michael Kracht, Jessica Rückert, Zoltan Varga, György Keri, Thomas F Schulz
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2013
Sujets:
Immunologic diseases. Allergy
RC581-607
Biology (General)
QH301-705.5
Accès en ligne:https://doaj.org/article/707952886d1c40bfac14803eee9b5773
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Internet

https://doaj.org/article/707952886d1c40bfac14803eee9b5773

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