Apoptosis of intestinal epithelial cells restricts Clostridium difficile infection in a model of pseudomembranous colitis
The enterotoxins TcdA and TcdB induce cytotoxicity of epithelial cells during Clostridium difficile infection. Here the authors show that bacterial induced epithelial cell death occurs via activation of caspases 3 and 7, resulting in apoptotic cell death.
Guardado en:
Autores principales: | Pedro H. V. Saavedra, Linyan Huang, Farzaneh Ghazavi, Stephanie Kourula, Tom Vanden Berghe, Nozomi Takahashi, Peter Vandenabeele, Mohamed Lamkanfi |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2018
|
Materias: | |
Acceso en línea: | https://doaj.org/article/708354e64dcb42588aa6882947904dbf |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Colitis fulminante asociada a Clostridium difficile
por: BANNURA C,GUILLERMO, et al.
Publicado: (2012) -
Successful Experience of Fecal Transplantation in a Patient with Severe Pseudomembranous Colitis
por: L. R. Shedoeva, et al.
Publicado: (2021) -
Cases of severe Clostridium difficile colitis proceeding with symptoms of peritonitis
por: E. I. Belinskaya
Publicado: (2015) -
Pseudomembranous Tracheobronchitis in an Immunocompetent Patient
por: Javier Navarro-Esteva, et al.
Publicado: (2021) -
Contaminación ambiental por Clostridium difficile
por: Riedel M,Gisela
Publicado: (2010)