Visceral Adiposity Associates With Malnutrition Risk Determined by Royal Free Hospital-Nutritional Prioritizing Tool in Cirrhosis

Mounting evidence has suggested the clinical significance of body composition abnormalities in the context of cirrhosis. Herein, we aimed to investigate the association between visceral adiposity and malnutrition risk in 176 hospitalized patients with cirrhosis. The adiposity parameters were obtaine...

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Autores principales:	Xiaoyu Wang, Yifan Li, Mingyu Sun, Gaoyue Guo, Wanting Yang, Yangyang Hui, Zihan Yu, Chaoqun Li, Xiaofei Fan, Bangmao Wang, Jie Zhang, Xingliang Zhao, Kui Jiang, Chao Sun
Formato:	article
Lenguaje:	EN
Publicado:	Frontiers Media S.A. 2021
Materias:	visceral adiposity cirrhosis malnutrition RFH-NPT visceral to subcutaneous adipose tissue area ratio Nutrition. Foods and food supply TX341-641
Acceso en línea:	https://doaj.org/article/70857fa71698432bbc0dc92bd3839a0b
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spelling	oai:doaj.org-article:70857fa71698432bbc0dc92bd3839a0b2021-11-30T18:25:32ZVisceral Adiposity Associates With Malnutrition Risk Determined by Royal Free Hospital-Nutritional Prioritizing Tool in Cirrhosis2296-861X10.3389/fnut.2021.766350https://doaj.org/article/70857fa71698432bbc0dc92bd3839a0b2021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fnut.2021.766350/fullhttps://doaj.org/toc/2296-861XMounting evidence has suggested the clinical significance of body composition abnormalities in the context of cirrhosis. Herein, we aimed to investigate the association between visceral adiposity and malnutrition risk in 176 hospitalized patients with cirrhosis. The adiposity parameters were obtained by computed tomography (CT) as follows: total adipose tissue index (TATI), visceral adipose tissue index (VATI), subcutaneous adipose tissue index (SATI), and visceral to subcutaneous adipose tissue area ratio (VSR). Malnutrition risk was screened using Royal Free Hospital-Nutritional Prioritizing Tool (RFH-NPT). Visceral adiposity was determined given a higher VSR based on our previously established cutoffs. Multivariate analysis implicated that male gender (OR = 2.884, 95% CI: 1.360–6.115, p = 0.006), BMI (OR = 0.879, 95% CI: 0.812–0.951, P = 0.001), albumin (OR = 0.934, 95% CI: 0.882–0.989, P = 0.019), and visceral adiposity (OR = 3.413, 95% CI: 1.344–8.670, P = 0.010) were independent risk factors of malnutrition risk. No significant difference was observed regarding TATI, SATI, and VATI among patients with low or moderate and high risk of malnutrition. In contrast, the proportion of male patients embracing visceral adiposity was higher in high malnutrition risk group compared with that in low or moderate group (47.27 vs. 17.86%, p = 0.009). Moreover, this disparity was of borderline statistical significance in women (19.05 vs. 5.88%, p = 0.061). Assessing adipose tissue distribution might potentiate the estimation of malnutrition risk in cirrhotics. It is pivotal to recognize visceral adiposity and develop targeted therapeutic strategies.Xiaoyu WangXiaoyu WangYifan LiYifan LiMingyu SunMingyu SunGaoyue GuoGaoyue GuoWanting YangWanting YangYangyang HuiYangyang HuiZihan YuZihan YuChaoqun LiChaoqun LiXiaofei FanXiaofei FanBangmao WangBangmao WangJie ZhangJie ZhangXingliang ZhaoXingliang ZhaoKui JiangKui JiangChao SunChao SunChao SunFrontiers Media S.A.articlevisceral adipositycirrhosismalnutritionRFH-NPTvisceral to subcutaneous adipose tissue area ratioNutrition. Foods and food supplyTX341-641ENFrontiers in Nutrition, Vol 8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	visceral adiposity cirrhosis malnutrition RFH-NPT visceral to subcutaneous adipose tissue area ratio Nutrition. Foods and food supply TX341-641
spellingShingle	visceral adiposity cirrhosis malnutrition RFH-NPT visceral to subcutaneous adipose tissue area ratio Nutrition. Foods and food supply TX341-641 Xiaoyu Wang Xiaoyu Wang Yifan Li Yifan Li Mingyu Sun Mingyu Sun Gaoyue Guo Gaoyue Guo Wanting Yang Wanting Yang Yangyang Hui Yangyang Hui Zihan Yu Zihan Yu Chaoqun Li Chaoqun Li Xiaofei Fan Xiaofei Fan Bangmao Wang Bangmao Wang Jie Zhang Jie Zhang Xingliang Zhao Xingliang Zhao Kui Jiang Kui Jiang Chao Sun Chao Sun Chao Sun Visceral Adiposity Associates With Malnutrition Risk Determined by Royal Free Hospital-Nutritional Prioritizing Tool in Cirrhosis
description	Mounting evidence has suggested the clinical significance of body composition abnormalities in the context of cirrhosis. Herein, we aimed to investigate the association between visceral adiposity and malnutrition risk in 176 hospitalized patients with cirrhosis. The adiposity parameters were obtained by computed tomography (CT) as follows: total adipose tissue index (TATI), visceral adipose tissue index (VATI), subcutaneous adipose tissue index (SATI), and visceral to subcutaneous adipose tissue area ratio (VSR). Malnutrition risk was screened using Royal Free Hospital-Nutritional Prioritizing Tool (RFH-NPT). Visceral adiposity was determined given a higher VSR based on our previously established cutoffs. Multivariate analysis implicated that male gender (OR = 2.884, 95% CI: 1.360–6.115, p = 0.006), BMI (OR = 0.879, 95% CI: 0.812–0.951, P = 0.001), albumin (OR = 0.934, 95% CI: 0.882–0.989, P = 0.019), and visceral adiposity (OR = 3.413, 95% CI: 1.344–8.670, P = 0.010) were independent risk factors of malnutrition risk. No significant difference was observed regarding TATI, SATI, and VATI among patients with low or moderate and high risk of malnutrition. In contrast, the proportion of male patients embracing visceral adiposity was higher in high malnutrition risk group compared with that in low or moderate group (47.27 vs. 17.86%, p = 0.009). Moreover, this disparity was of borderline statistical significance in women (19.05 vs. 5.88%, p = 0.061). Assessing adipose tissue distribution might potentiate the estimation of malnutrition risk in cirrhotics. It is pivotal to recognize visceral adiposity and develop targeted therapeutic strategies.
format	article
author	Xiaoyu Wang Xiaoyu Wang Yifan Li Yifan Li Mingyu Sun Mingyu Sun Gaoyue Guo Gaoyue Guo Wanting Yang Wanting Yang Yangyang Hui Yangyang Hui Zihan Yu Zihan Yu Chaoqun Li Chaoqun Li Xiaofei Fan Xiaofei Fan Bangmao Wang Bangmao Wang Jie Zhang Jie Zhang Xingliang Zhao Xingliang Zhao Kui Jiang Kui Jiang Chao Sun Chao Sun Chao Sun
author_facet	Xiaoyu Wang Xiaoyu Wang Yifan Li Yifan Li Mingyu Sun Mingyu Sun Gaoyue Guo Gaoyue Guo Wanting Yang Wanting Yang Yangyang Hui Yangyang Hui Zihan Yu Zihan Yu Chaoqun Li Chaoqun Li Xiaofei Fan Xiaofei Fan Bangmao Wang Bangmao Wang Jie Zhang Jie Zhang Xingliang Zhao Xingliang Zhao Kui Jiang Kui Jiang Chao Sun Chao Sun Chao Sun
author_sort	Xiaoyu Wang
title	Visceral Adiposity Associates With Malnutrition Risk Determined by Royal Free Hospital-Nutritional Prioritizing Tool in Cirrhosis
title_short	Visceral Adiposity Associates With Malnutrition Risk Determined by Royal Free Hospital-Nutritional Prioritizing Tool in Cirrhosis
title_full	Visceral Adiposity Associates With Malnutrition Risk Determined by Royal Free Hospital-Nutritional Prioritizing Tool in Cirrhosis
title_fullStr	Visceral Adiposity Associates With Malnutrition Risk Determined by Royal Free Hospital-Nutritional Prioritizing Tool in Cirrhosis
title_full_unstemmed	Visceral Adiposity Associates With Malnutrition Risk Determined by Royal Free Hospital-Nutritional Prioritizing Tool in Cirrhosis
title_sort	visceral adiposity associates with malnutrition risk determined by royal free hospital-nutritional prioritizing tool in cirrhosis
publisher	Frontiers Media S.A.
publishDate	2021
url	https://doaj.org/article/70857fa71698432bbc0dc92bd3839a0b
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Visceral Adiposity Associates With Malnutrition Risk Determined by Royal Free Hospital-Nutritional Prioritizing Tool in Cirrhosis

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