Relationship of hypoglycemia and glucose variability with autonomic dysfunction in children and adolescents with type 1 diabetes

Aim. Glucose variability (GV) and hypoglycaemia frequency and duration, depending on cardiovascular autonomic dysfunction, in children and adolescents with type 1 diabetes mellitus (T1DM) were evaluated. Materials and methods. One hundred and thirty T1DM patients, aged 6?18 years, were included in...

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Autor principal:	Dmitriy Nikitich Laptev
Formato:	article
Lenguaje:	EN RU
Publicado:	Endocrinology Research Centre 2014
Materias:	type 1 diabetes mellitus, autonomic neuropathy, heart rate variability, hypoglycaemia, glucose variability, qt interval Nutritional diseases. Deficiency diseases RC620-627
Acceso en línea:	https://doaj.org/article/708712bc7f594ddb8dca8532d9dd506f
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spelling	oai:doaj.org-article:708712bc7f594ddb8dca8532d9dd506f2021-11-14T09:00:19ZRelationship of hypoglycemia and glucose variability with autonomic dysfunction in children and adolescents with type 1 diabetes2072-03512072-037810.14341/DM2014487-92https://doaj.org/article/708712bc7f594ddb8dca8532d9dd506f2014-12-01T00:00:00Zhttps://www.dia-endojournals.ru/jour/article/view/6699https://doaj.org/toc/2072-0351https://doaj.org/toc/2072-0378Aim. Glucose variability (GV) and hypoglycaemia frequency and duration, depending on cardiovascular autonomic dysfunction, in children and adolescents with type 1 diabetes mellitus (T1DM) were evaluated. Materials and methods. One hundred and thirty T1DM patients, aged 6?18 years, were included in this study. The study included 3 tests:. continuous glucose monitoring (CGM) with GV evaluation, frequency and duration of hypoglycaemia;24-h ECG monitoring with automatic calculation of QTc interval and heart rate variability (HRV) parameters;cardiovascular autonomic tests.Results. The estimated prevalence of cardiovascular autonomic neuropathy (CAN) was 19.2%. CAN positive (CAN+) patients had lower values from cardiovascular autonomic tests and HRV and longer QTc intervals compared with CAN negative (CAN-) patients (pDmitriy Nikitich LaptevEndocrinology Research Centrearticletype 1 diabetes mellitus, autonomic neuropathy, heart rate variability, hypoglycaemia, glucose variability, qt intervalNutritional diseases. Deficiency diseasesRC620-627ENRUСахарный диабет, Vol 17, Iss 4, Pp 87-92 (2014)
institution	DOAJ
collection	DOAJ
language	EN RU
topic	type 1 diabetes mellitus, autonomic neuropathy, heart rate variability, hypoglycaemia, glucose variability, qt interval Nutritional diseases. Deficiency diseases RC620-627
spellingShingle	type 1 diabetes mellitus, autonomic neuropathy, heart rate variability, hypoglycaemia, glucose variability, qt interval Nutritional diseases. Deficiency diseases RC620-627 Dmitriy Nikitich Laptev Relationship of hypoglycemia and glucose variability with autonomic dysfunction in children and adolescents with type 1 diabetes
description	Aim. Glucose variability (GV) and hypoglycaemia frequency and duration, depending on cardiovascular autonomic dysfunction, in children and adolescents with type 1 diabetes mellitus (T1DM) were evaluated. Materials and methods. One hundred and thirty T1DM patients, aged 6?18 years, were included in this study. The study included 3 tests:. continuous glucose monitoring (CGM) with GV evaluation, frequency and duration of hypoglycaemia;24-h ECG monitoring with automatic calculation of QTc interval and heart rate variability (HRV) parameters;cardiovascular autonomic tests.Results. The estimated prevalence of cardiovascular autonomic neuropathy (CAN) was 19.2%. CAN positive (CAN+) patients had lower values from cardiovascular autonomic tests and HRV and longer QTc intervals compared with CAN negative (CAN-) patients (p
format	article
author	Dmitriy Nikitich Laptev
author_facet	Dmitriy Nikitich Laptev
author_sort	Dmitriy Nikitich Laptev
title	Relationship of hypoglycemia and glucose variability with autonomic dysfunction in children and adolescents with type 1 diabetes
title_short	Relationship of hypoglycemia and glucose variability with autonomic dysfunction in children and adolescents with type 1 diabetes
title_full	Relationship of hypoglycemia and glucose variability with autonomic dysfunction in children and adolescents with type 1 diabetes
title_fullStr	Relationship of hypoglycemia and glucose variability with autonomic dysfunction in children and adolescents with type 1 diabetes
title_full_unstemmed	Relationship of hypoglycemia and glucose variability with autonomic dysfunction in children and adolescents with type 1 diabetes
title_sort	relationship of hypoglycemia and glucose variability with autonomic dysfunction in children and adolescents with type 1 diabetes
publisher	Endocrinology Research Centre
publishDate	2014
url	https://doaj.org/article/708712bc7f594ddb8dca8532d9dd506f
work_keys_str_mv	AT dmitriynikitichlaptev relationshipofhypoglycemiaandglucosevariabilitywithautonomicdysfunctioninchildrenandadolescentswithtype1diabetes
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Relationship of hypoglycemia and glucose variability with autonomic dysfunction in children and adolescents with type 1 diabetes

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