Strong association of type 2 diabetes with degenerative lumbar spine disorders

Abstract Tantalizing connections between type 2 diabetes and degenerative lumbar spine disorders have become increasingly evident. However, the association of type 2 diabetes with degenerative lumbar spine disorders remains unclear. We sought to clarify the association between type 2 diabetes and lu...

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Autores principales:	Chul-Hyun Park, Kyoung-Bok Min, Jin-Young Min, Du Hwan Kim, Kyung Mook Seo, Don-Kyu Kim
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/7089263fa0884b0cad32e8966b704420
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spelling	oai:doaj.org-article:7089263fa0884b0cad32e8966b7044202021-12-02T16:27:45ZStrong association of type 2 diabetes with degenerative lumbar spine disorders10.1038/s41598-021-95626-y2045-2322https://doaj.org/article/7089263fa0884b0cad32e8966b7044202021-08-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-95626-yhttps://doaj.org/toc/2045-2322Abstract Tantalizing connections between type 2 diabetes and degenerative lumbar spine disorders have become increasingly evident. However, the association of type 2 diabetes with degenerative lumbar spine disorders remains unclear. We sought to clarify the association between type 2 diabetes and lumbar spine disorders using nationwide data in Korea. Furthermore, we explored the association of diabetes with the prevalence of spinal procedures. The data in this study was obtained from Korean health claim database. Between 2016 and 2019, totals of 479,680 diabetes and 479,680 age- and sex-matched control subjects were enrolled. Patients with diabetes had more likely to have degenerative lumbar spine disorders and spinal procedures than controls. Using multivariate-adjusted analysis, patients with diabetes were at increased risk of being concomitantly affected by lumbar disc disorder [adjusted odds ratio 1.11 (95% confidence interval 1.10–1.12)], lumbar spondylotic radiculopathy [1.12 (1.11–1.13)], spondylolisthesis [1.05 (1.02–1.08)] and spinal stenosis [1.16 (1.15–1.18)], compared to controls. Furthermore, diabetic patients had an increased risk of undergoing lumbar spinal injection [1.13 (1.12–1.14)], laminectomy [1.19 (1.15–1.23)], and fusion surgery [1.35 (1.29–1.42)]. We demonstrated that type 2 diabetes was significantly associated with lumbar spine disorders and frequent spinal procedures. Our results suggest diabetes as a predisposing factor for lumbar spine disorders.Chul-Hyun ParkKyoung-Bok MinJin-Young MinDu Hwan KimKyung Mook SeoDon-Kyu KimNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Chul-Hyun Park Kyoung-Bok Min Jin-Young Min Du Hwan Kim Kyung Mook Seo Don-Kyu Kim Strong association of type 2 diabetes with degenerative lumbar spine disorders
description	Abstract Tantalizing connections between type 2 diabetes and degenerative lumbar spine disorders have become increasingly evident. However, the association of type 2 diabetes with degenerative lumbar spine disorders remains unclear. We sought to clarify the association between type 2 diabetes and lumbar spine disorders using nationwide data in Korea. Furthermore, we explored the association of diabetes with the prevalence of spinal procedures. The data in this study was obtained from Korean health claim database. Between 2016 and 2019, totals of 479,680 diabetes and 479,680 age- and sex-matched control subjects were enrolled. Patients with diabetes had more likely to have degenerative lumbar spine disorders and spinal procedures than controls. Using multivariate-adjusted analysis, patients with diabetes were at increased risk of being concomitantly affected by lumbar disc disorder [adjusted odds ratio 1.11 (95% confidence interval 1.10–1.12)], lumbar spondylotic radiculopathy [1.12 (1.11–1.13)], spondylolisthesis [1.05 (1.02–1.08)] and spinal stenosis [1.16 (1.15–1.18)], compared to controls. Furthermore, diabetic patients had an increased risk of undergoing lumbar spinal injection [1.13 (1.12–1.14)], laminectomy [1.19 (1.15–1.23)], and fusion surgery [1.35 (1.29–1.42)]. We demonstrated that type 2 diabetes was significantly associated with lumbar spine disorders and frequent spinal procedures. Our results suggest diabetes as a predisposing factor for lumbar spine disorders.
format	article
author	Chul-Hyun Park Kyoung-Bok Min Jin-Young Min Du Hwan Kim Kyung Mook Seo Don-Kyu Kim
author_facet	Chul-Hyun Park Kyoung-Bok Min Jin-Young Min Du Hwan Kim Kyung Mook Seo Don-Kyu Kim
author_sort	Chul-Hyun Park
title	Strong association of type 2 diabetes with degenerative lumbar spine disorders
title_short	Strong association of type 2 diabetes with degenerative lumbar spine disorders
title_full	Strong association of type 2 diabetes with degenerative lumbar spine disorders
title_fullStr	Strong association of type 2 diabetes with degenerative lumbar spine disorders
title_full_unstemmed	Strong association of type 2 diabetes with degenerative lumbar spine disorders
title_sort	strong association of type 2 diabetes with degenerative lumbar spine disorders
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/7089263fa0884b0cad32e8966b704420
work_keys_str_mv	AT chulhyunpark strongassociationoftype2diabeteswithdegenerativelumbarspinedisorders AT kyoungbokmin strongassociationoftype2diabeteswithdegenerativelumbarspinedisorders AT jinyoungmin strongassociationoftype2diabeteswithdegenerativelumbarspinedisorders AT duhwankim strongassociationoftype2diabeteswithdegenerativelumbarspinedisorders AT kyungmookseo strongassociationoftype2diabeteswithdegenerativelumbarspinedisorders AT donkyukim strongassociationoftype2diabeteswithdegenerativelumbarspinedisorders
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Strong association of type 2 diabetes with degenerative lumbar spine disorders

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