Prevention of pancreatic acinar cell carcinoma by Roux-en-Y Gastric Bypass Surgery

Prevention of pancreatic acinar cell carcinoma by Roux-en-Y Gastric Bypass Surgery

Pancreatic cancer risk increases in obese and diabetic people. In this manuscript, the authors show that Roux-en-Y gastric bypass surgery (RYGB) decreases the impact of pancreatic cancer in a mouse model; this effect seems independent of weight loss or decreased hyperglycemia pointing to an involvem...

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Autores principales: Rui He, Yue Yin, Wenzhen Yin, Yin Li, Jing Zhao, Weizhen Zhang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/70899d1993ef44389b264b81f3f11a5f
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spelling oai:doaj.org-article:70899d1993ef44389b264b81f3f11a5f2021-12-02T17:33:17ZPrevention of pancreatic acinar cell carcinoma by Roux-en-Y Gastric Bypass Surgery10.1038/s41467-018-06571-w2041-1723https://doaj.org/article/70899d1993ef44389b264b81f3f11a5f2018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06571-whttps://doaj.org/toc/2041-1723Pancreatic cancer risk increases in obese and diabetic people. In this manuscript, the authors show that Roux-en-Y gastric bypass surgery (RYGB) decreases the impact of pancreatic cancer in a mouse model; this effect seems independent of weight loss or decreased hyperglycemia pointing to an involvement of mTOR pathway.Rui HeYue YinWenzhen YinYin LiJing ZhaoWeizhen ZhangNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-7 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Rui He
Yue Yin
Wenzhen Yin
Yin Li
Jing Zhao
Weizhen Zhang
Prevention of pancreatic acinar cell carcinoma by Roux-en-Y Gastric Bypass Surgery
description Pancreatic cancer risk increases in obese and diabetic people. In this manuscript, the authors show that Roux-en-Y gastric bypass surgery (RYGB) decreases the impact of pancreatic cancer in a mouse model; this effect seems independent of weight loss or decreased hyperglycemia pointing to an involvement of mTOR pathway.
format article
author Rui He
Yue Yin
Wenzhen Yin
Yin Li
Jing Zhao
Weizhen Zhang
author_facet Rui He
Yue Yin
Wenzhen Yin
Yin Li
Jing Zhao
Weizhen Zhang
author_sort Rui He
title Prevention of pancreatic acinar cell carcinoma by Roux-en-Y Gastric Bypass Surgery
title_short Prevention of pancreatic acinar cell carcinoma by Roux-en-Y Gastric Bypass Surgery
title_full Prevention of pancreatic acinar cell carcinoma by Roux-en-Y Gastric Bypass Surgery
title_fullStr Prevention of pancreatic acinar cell carcinoma by Roux-en-Y Gastric Bypass Surgery
title_full_unstemmed Prevention of pancreatic acinar cell carcinoma by Roux-en-Y Gastric Bypass Surgery
title_sort prevention of pancreatic acinar cell carcinoma by roux-en-y gastric bypass surgery
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/70899d1993ef44389b264b81f3f11a5f
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AT yueyin preventionofpancreaticacinarcellcarcinomabyrouxenygastricbypasssurgery
AT wenzhenyin preventionofpancreaticacinarcellcarcinomabyrouxenygastricbypasssurgery
AT yinli preventionofpancreaticacinarcellcarcinomabyrouxenygastricbypasssurgery
AT jingzhao preventionofpancreaticacinarcellcarcinomabyrouxenygastricbypasssurgery
AT weizhenzhang preventionofpancreaticacinarcellcarcinomabyrouxenygastricbypasssurgery
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