Sensing of Bacterial Type IV Secretion via the Unfolded Protein Response

ABSTRACT Host cytokine responses to Brucella abortus infection are elicited predominantly by the deployment of a type IV secretion system (T4SS). However, the mechanism by which the T4SS elicits inflammation remains unknown. Here we show that translocation of the T4SS substrate VceC into host cells...

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Bibliographic Details
Main Authors: Maarten F. de Jong, Tregei Starr, Maria G. Winter, Andreas B. den Hartigh, Robert Child, Leigh A. Knodler, Jan Maarten van Dijl, Jean Celli, Renée M. Tsolis
Format: article
Language:EN
Published: American Society for Microbiology 2013
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Online Access:https://doaj.org/article/708e716606f1474fb06f4ac852025a7a
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