TRPV1 SUMOylation regulates nociceptive signaling in models of inflammatory pain

SUMOylation is a post translational modification. Here the authors show that TRPV1, which conveys thermal nociception, is SUMOylated in DRGs in inflammatory conditions and contributes to pain behavior in mice.

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Autores principales:	Yan Wang, Yingwei Gao, Quan Tian, Qi Deng, Yangbo Wang, Tian Zhou, Qiang Liu, Kaidi Mei, Yingping Wang, Huiqing Liu, Ruining Ma, Yuqiang Ding, Weifang Rong, Jinke Cheng, Jing Yao, Tian-Le Xu, Michael X. Zhu, Yong Li
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/708eecdc1ce64a788e79adeb654237bd
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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spelling	oai:doaj.org-article:708eecdc1ce64a788e79adeb654237bd2021-12-02T17:31:46ZTRPV1 SUMOylation regulates nociceptive signaling in models of inflammatory pain10.1038/s41467-018-03974-72041-1723https://doaj.org/article/708eecdc1ce64a788e79adeb654237bd2018-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03974-7https://doaj.org/toc/2041-1723SUMOylation is a post translational modification. Here the authors show that TRPV1, which conveys thermal nociception, is SUMOylated in DRGs in inflammatory conditions and contributes to pain behavior in mice.Yan WangYingwei GaoQuan TianQi DengYangbo WangTian ZhouQiang LiuKaidi MeiYingping WangHuiqing LiuRuining MaYuqiang DingWeifang RongJinke ChengJing YaoTian-Le XuMichael X. ZhuYong LiNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Yan Wang Yingwei Gao Quan Tian Qi Deng Yangbo Wang Tian Zhou Qiang Liu Kaidi Mei Yingping Wang Huiqing Liu Ruining Ma Yuqiang Ding Weifang Rong Jinke Cheng Jing Yao Tian-Le Xu Michael X. Zhu Yong Li TRPV1 SUMOylation regulates nociceptive signaling in models of inflammatory pain
description	SUMOylation is a post translational modification. Here the authors show that TRPV1, which conveys thermal nociception, is SUMOylated in DRGs in inflammatory conditions and contributes to pain behavior in mice.
format	article
author	Yan Wang Yingwei Gao Quan Tian Qi Deng Yangbo Wang Tian Zhou Qiang Liu Kaidi Mei Yingping Wang Huiqing Liu Ruining Ma Yuqiang Ding Weifang Rong Jinke Cheng Jing Yao Tian-Le Xu Michael X. Zhu Yong Li
author_facet	Yan Wang Yingwei Gao Quan Tian Qi Deng Yangbo Wang Tian Zhou Qiang Liu Kaidi Mei Yingping Wang Huiqing Liu Ruining Ma Yuqiang Ding Weifang Rong Jinke Cheng Jing Yao Tian-Le Xu Michael X. Zhu Yong Li
author_sort	Yan Wang
title	TRPV1 SUMOylation regulates nociceptive signaling in models of inflammatory pain
title_short	TRPV1 SUMOylation regulates nociceptive signaling in models of inflammatory pain
title_full	TRPV1 SUMOylation regulates nociceptive signaling in models of inflammatory pain
title_fullStr	TRPV1 SUMOylation regulates nociceptive signaling in models of inflammatory pain
title_full_unstemmed	TRPV1 SUMOylation regulates nociceptive signaling in models of inflammatory pain
title_sort	trpv1 sumoylation regulates nociceptive signaling in models of inflammatory pain
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/708eecdc1ce64a788e79adeb654237bd
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TRPV1 SUMOylation regulates nociceptive signaling in models of inflammatory pain

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