βig-h3 promotes human osteosarcoma cells metastasis by interacting with integrin α2β1 and activating PI3K signaling pathway.

Osteosarcoma, the most common primary bone tumor in children and young adolescents, is characterized by local invasion and distant metastasis. But the detailed mechanisms of osteosarcoma metastasis are not well known. In the present study, we found that βig-h3 promotes metastatic potential of human...

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Auteurs principaux: Yun-Shan Guo, Rui Zhao, Jie Ma, Wei Cui, Zhen Sun, Bo Gao, Shu He, Yue-Hu Han, Jing Fan, Liu Yang, Juan Tang, Zhuo-Jing Luo
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2014
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Accès en ligne:https://doaj.org/article/7094d3175398471388d95b5807a0248c
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