Serum αFP Level in Cord Blood of Full Term Neonates Born in Babol City

BACKGROUNDANDOBJECTIVE: Serum alpha-fetoprotein (αFP) level is considered as a diagnostic marker is higher than normal in many congenital tumors such as germ cell, hepatoblastoma, as well as liver and metabolic diseases in neonates. Normal neonates also have a higher level of alpha-fetoprotein than...

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Autores principales:	Y Zahedpasha, A Tamaddoni, M Ahmadpour-kacho, S Pourmoghtader
Formato:	article
Lenguaje:	EN FA
Publicado:	Babol University of Medical Sciences 2019
Materias:	alfa-fetoprotein newborn umbilical cord blood Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/709b0f336dc94c60b6515437ab1d4546
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spelling	oai:doaj.org-article:709b0f336dc94c60b6515437ab1d45462021-11-10T08:30:36ZSerum αFP Level in Cord Blood of Full Term Neonates Born in Babol City1561-41072251-7170https://doaj.org/article/709b0f336dc94c60b6515437ab1d45462019-12-01T00:00:00Zhttp://jbums.org/article-1-8256-en.htmlhttps://doaj.org/toc/1561-4107https://doaj.org/toc/2251-7170BACKGROUNDANDOBJECTIVE: Serum alpha-fetoprotein (αFP) level is considered as a diagnostic marker is higher than normal in many congenital tumors such as germ cell, hepatoblastoma, as well as liver and metabolic diseases in neonates. Normal neonates also have a higher level of alpha-fetoprotein than others, so it is important to diagnose this interference. In valid sources, the normal serum alpha-fetoprotein level in infants is related to advanced countries, which may vary in our country. Therefore, this study was conducted to determine the serum levels of alpha-fetoprotein in the umbilical cord blood of term neonates born in Babol and to compare them in two genders. METHODS: This cross-sectional study was performed on 500 neonates (37-42 weeks) born in hospitals in Babol city where physical examination was normal. At birth, 5 ml of umbilical cord blood was taken and samples were sent to the lab for measurement of alpha-fetoprotein. Serum alpha-fetoprotein level was measured by ELISA method and was compared in two genders. FINDINGS: Mean serum a FP levels was 76.57±35.25 ng/ml (range 2.3-160) and it was significantly higher in males (80.54±36.95 vs. 73.69±33.73 ng/ml) which was statistically significant (p=0.002). CONCLUSION: The results of this study showed that the level of alpha-fetoprotein in neonates born in Babol is relatively high and also in males is more than females.Y ZahedpashaA TamaddoniM Ahmadpour-kachoS PourmoghtaderBabol University of Medical Sciencesarticlealfa-fetoproteinnewbornumbilical cord bloodMedicineRMedicine (General)R5-920ENFAMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, Vol 21, Iss 1, Pp 135-139 (2019)
institution	DOAJ
collection	DOAJ
language	EN FA
topic	alfa-fetoprotein newborn umbilical cord blood Medicine R Medicine (General) R5-920
spellingShingle	alfa-fetoprotein newborn umbilical cord blood Medicine R Medicine (General) R5-920 Y Zahedpasha A Tamaddoni M Ahmadpour-kacho S Pourmoghtader Serum αFP Level in Cord Blood of Full Term Neonates Born in Babol City
description	BACKGROUNDANDOBJECTIVE: Serum alpha-fetoprotein (αFP) level is considered as a diagnostic marker is higher than normal in many congenital tumors such as germ cell, hepatoblastoma, as well as liver and metabolic diseases in neonates. Normal neonates also have a higher level of alpha-fetoprotein than others, so it is important to diagnose this interference. In valid sources, the normal serum alpha-fetoprotein level in infants is related to advanced countries, which may vary in our country. Therefore, this study was conducted to determine the serum levels of alpha-fetoprotein in the umbilical cord blood of term neonates born in Babol and to compare them in two genders. METHODS: This cross-sectional study was performed on 500 neonates (37-42 weeks) born in hospitals in Babol city where physical examination was normal. At birth, 5 ml of umbilical cord blood was taken and samples were sent to the lab for measurement of alpha-fetoprotein. Serum alpha-fetoprotein level was measured by ELISA method and was compared in two genders. FINDINGS: Mean serum a FP levels was 76.57±35.25 ng/ml (range 2.3-160) and it was significantly higher in males (80.54±36.95 vs. 73.69±33.73 ng/ml) which was statistically significant (p=0.002). CONCLUSION: The results of this study showed that the level of alpha-fetoprotein in neonates born in Babol is relatively high and also in males is more than females.
format	article
author	Y Zahedpasha A Tamaddoni M Ahmadpour-kacho S Pourmoghtader
author_facet	Y Zahedpasha A Tamaddoni M Ahmadpour-kacho S Pourmoghtader
author_sort	Y Zahedpasha
title	Serum αFP Level in Cord Blood of Full Term Neonates Born in Babol City
title_short	Serum αFP Level in Cord Blood of Full Term Neonates Born in Babol City
title_full	Serum αFP Level in Cord Blood of Full Term Neonates Born in Babol City
title_fullStr	Serum αFP Level in Cord Blood of Full Term Neonates Born in Babol City
title_full_unstemmed	Serum αFP Level in Cord Blood of Full Term Neonates Born in Babol City
title_sort	serum αfp level in cord blood of full term neonates born in babol city
publisher	Babol University of Medical Sciences
publishDate	2019
url	https://doaj.org/article/709b0f336dc94c60b6515437ab1d4546
work_keys_str_mv	AT yzahedpasha serumafplevelincordbloodoffulltermneonatesborninbabolcity AT atamaddoni serumafplevelincordbloodoffulltermneonatesborninbabolcity AT mahmadpourkacho serumafplevelincordbloodoffulltermneonatesborninbabolcity AT spourmoghtader serumafplevelincordbloodoffulltermneonatesborninbabolcity
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Serum αFP Level in Cord Blood of Full Term Neonates Born in Babol City

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