Hypoxic regulation of the expression of genes encoded estrogen related proteins in U87 glioma cells: eff ect of IRE1 inhibition

Objective. The aim of the present study was to examine the effect of inhibition of endoplasmic reticulum stress signaling, mediated by IRE1 (inositol requiring enzyme 1), which is a central mediator of the unfolded protein response on the expression of genes encoded estrogen related proteins (NRIP1/...

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Autores principales:	Do Minchenko, Oo Riabovol, Oo Ratushna, Oh Minchenko
Formato:	article
Lenguaje:	EN
Publicado:	Sciendo 2017
Materias:	ire1 inhibition hypoxia mrna expression nrip1 ebbp esrra e2ig5 pgrmc2 slc39a6 u87 glioma cells Diseases of the endocrine glands. Clinical endocrinology RC648-665
Acceso en línea:	https://doaj.org/article/70a27e5731fe4abeb20055ec27249b92
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spelling	oai:doaj.org-article:70a27e5731fe4abeb20055ec27249b922021-12-02T16:33:01ZHypoxic regulation of the expression of genes encoded estrogen related proteins in U87 glioma cells: eff ect of IRE1 inhibition1336-032910.1515/enr-2017-0002https://doaj.org/article/70a27e5731fe4abeb20055ec27249b922017-01-01T00:00:00Zhttps://doi.org/10.1515/enr-2017-0002https://doaj.org/toc/1336-0329Objective. The aim of the present study was to examine the effect of inhibition of endoplasmic reticulum stress signaling, mediated by IRE1 (inositol requiring enzyme 1), which is a central mediator of the unfolded protein response on the expression of genes encoded estrogen related proteins (NRIP1/RIP140, TRIM16/EBBP, ESRRA/NR3B1, FAM162A/E2IG5, PGRMC2/PMBP, and SLC39A6/LIV-1) and their hypoxic regulation in U87 glioma cells for evaluation of their possible significance in the control of glioma cells proliferation.Do MinchenkoOo RiabovolOo RatushnaOh MinchenkoSciendoarticleire1 inhibitionhypoxiamrna expressionnrip1ebbpesrrae2ig5pgrmc2slc39a6u87 glioma cellsDiseases of the endocrine glands. Clinical endocrinologyRC648-665ENEndocrine Regulations, Vol 51, Iss 1, Pp 8-19 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	ire1 inhibition hypoxia mrna expression nrip1 ebbp esrra e2ig5 pgrmc2 slc39a6 u87 glioma cells Diseases of the endocrine glands. Clinical endocrinology RC648-665
spellingShingle	ire1 inhibition hypoxia mrna expression nrip1 ebbp esrra e2ig5 pgrmc2 slc39a6 u87 glioma cells Diseases of the endocrine glands. Clinical endocrinology RC648-665 Do Minchenko Oo Riabovol Oo Ratushna Oh Minchenko Hypoxic regulation of the expression of genes encoded estrogen related proteins in U87 glioma cells: eff ect of IRE1 inhibition
description	Objective. The aim of the present study was to examine the effect of inhibition of endoplasmic reticulum stress signaling, mediated by IRE1 (inositol requiring enzyme 1), which is a central mediator of the unfolded protein response on the expression of genes encoded estrogen related proteins (NRIP1/RIP140, TRIM16/EBBP, ESRRA/NR3B1, FAM162A/E2IG5, PGRMC2/PMBP, and SLC39A6/LIV-1) and their hypoxic regulation in U87 glioma cells for evaluation of their possible significance in the control of glioma cells proliferation.
format	article
author	Do Minchenko Oo Riabovol Oo Ratushna Oh Minchenko
author_facet	Do Minchenko Oo Riabovol Oo Ratushna Oh Minchenko
author_sort	Do Minchenko
title	Hypoxic regulation of the expression of genes encoded estrogen related proteins in U87 glioma cells: eff ect of IRE1 inhibition
title_short	Hypoxic regulation of the expression of genes encoded estrogen related proteins in U87 glioma cells: eff ect of IRE1 inhibition
title_full	Hypoxic regulation of the expression of genes encoded estrogen related proteins in U87 glioma cells: eff ect of IRE1 inhibition
title_fullStr	Hypoxic regulation of the expression of genes encoded estrogen related proteins in U87 glioma cells: eff ect of IRE1 inhibition
title_full_unstemmed	Hypoxic regulation of the expression of genes encoded estrogen related proteins in U87 glioma cells: eff ect of IRE1 inhibition
title_sort	hypoxic regulation of the expression of genes encoded estrogen related proteins in u87 glioma cells: eff ect of ire1 inhibition
publisher	Sciendo
publishDate	2017
url	https://doaj.org/article/70a27e5731fe4abeb20055ec27249b92
work_keys_str_mv	AT dominchenko hypoxicregulationoftheexpressionofgenesencodedestrogenrelatedproteinsinu87gliomacellseffectofire1inhibition AT ooriabovol hypoxicregulationoftheexpressionofgenesencodedestrogenrelatedproteinsinu87gliomacellseffectofire1inhibition AT ooratushna hypoxicregulationoftheexpressionofgenesencodedestrogenrelatedproteinsinu87gliomacellseffectofire1inhibition AT ohminchenko hypoxicregulationoftheexpressionofgenesencodedestrogenrelatedproteinsinu87gliomacellseffectofire1inhibition
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Hypoxic regulation of the expression of genes encoded estrogen related proteins in U87 glioma cells: eff ect of IRE1 inhibition

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