Myocardial pathology induced by aldosterone is dependent on non-canonical activities of G protein-coupled receptor kinases
High aldosterone levels cause heart damage independently of its well-known effect on blood pressure. Here, Cannavo et al. show that aldosterone-mediated cardiac pathology involves G protein-coupled receptor (GPCR) kinase 2 (GRK2) and GRK5 that integrate signals from angiotensin II receptor (AT1R).
Enregistré dans:
| Auteurs principaux: | , , , , , , , , , , |
|---|---|
| Format: | article |
| Langue: | EN |
| Publié: |
Nature Portfolio
2016
|
| Sujets: | |
| Accès en ligne: | https://doaj.org/article/70ab970e75e145a7b7e6fbb932036a1c |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|