Normal Levels of TSH Affect the Metabolic Profile Differently in Physically Active Males and Females

Our study was aimed at the evaluation of relationships between thyroid stimulating hormone (TSH) within the normal range and metabolic risk factors (glucose, insulin, HOMA-IR and lipoprotein profile) in physically active male and female students. In 219 students circulating TSH, glucose, insulin and...

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Autores principales:	Marzena Malara, Anna Kęska, Joanna Tkaczyk, Grażyna Lutosławska
Formato:	article
Lenguaje:	EN
Publicado:	Wydawnictwo Naukowe Uniwersytetu Szczecińskiego 2021
Materias:	normal range TSH glucose insulin HOMA-IR lipoproteins Sports GV557-1198.995 Sports medicine RC1200-1245 Physiology QP1-981
Acceso en línea:	https://doaj.org/article/70afe74d3ee24bc29116f9993dce6669
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spelling	oai:doaj.org-article:70afe74d3ee24bc29116f9993dce66692021-11-29T11:03:18ZNormal Levels of TSH Affect the Metabolic Profile Differently in Physically Active Males and Females10.18276/cej.2021.3-042300-9705https://doaj.org/article/70afe74d3ee24bc29116f9993dce66692021-01-01T00:00:00Zhttps://wnus.edu.pl/cejssm/en/issue/1210/article/19265/https://doaj.org/toc/2300-9705Our study was aimed at the evaluation of relationships between thyroid stimulating hormone (TSH) within the normal range and metabolic risk factors (glucose, insulin, HOMA-IR and lipoprotein profile) in physically active male and female students. In 219 students circulating TSH, glucose, insulin and lipoproteins were measured in blood under fasting conditions. Insulin resistance was expressed as HOMA-IR (homeostasis model assessment for insulin resistance). For further procedures 99 males and 97 regularly menstruating females with TSH 0.4–4.0 μIU/ml were accepted. In male students no correlations between circulating TSH, anthropometric and biochemical variables were noted. In females TSH within the normal range was slightly but significantly correlated with the triglyceride (TG) level (p < 0.03). However, step-wise multiple regression analysis revealed that the effect of TSH was small (p < 0.046) in relation to that found for HOMA-IR ( p < 0.0009). No relationships between biochemical variables and normal levels of TSH were noted in male students. However, surprisingly normal range TSH in males was slightly but significantly correlated with the percentage of body fat and this issue needs further studies concerning measurements of different fat depots. The above data suggests that in active females TG synthesis and export from the liver is more sensitive to TSH action than in active male counterparts.Marzena MalaraAnna KęskaJoanna TkaczykGrażyna LutosławskaWydawnictwo Naukowe Uniwersytetu Szczecińskiegoarticlenormal range TSHglucoseinsulinHOMA-IRlipoproteinsSportsGV557-1198.995Sports medicineRC1200-1245PhysiologyQP1-981ENCentral European Journal of Sport Sciences and Medicine, Vol 35 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	normal range TSH glucose insulin HOMA-IR lipoproteins Sports GV557-1198.995 Sports medicine RC1200-1245 Physiology QP1-981
spellingShingle	normal range TSH glucose insulin HOMA-IR lipoproteins Sports GV557-1198.995 Sports medicine RC1200-1245 Physiology QP1-981 Marzena Malara Anna Kęska Joanna Tkaczyk Grażyna Lutosławska Normal Levels of TSH Affect the Metabolic Profile Differently in Physically Active Males and Females
description	Our study was aimed at the evaluation of relationships between thyroid stimulating hormone (TSH) within the normal range and metabolic risk factors (glucose, insulin, HOMA-IR and lipoprotein profile) in physically active male and female students. In 219 students circulating TSH, glucose, insulin and lipoproteins were measured in blood under fasting conditions. Insulin resistance was expressed as HOMA-IR (homeostasis model assessment for insulin resistance). For further procedures 99 males and 97 regularly menstruating females with TSH 0.4–4.0 μIU/ml were accepted. In male students no correlations between circulating TSH, anthropometric and biochemical variables were noted. In females TSH within the normal range was slightly but significantly correlated with the triglyceride (TG) level (p < 0.03). However, step-wise multiple regression analysis revealed that the effect of TSH was small (p < 0.046) in relation to that found for HOMA-IR ( p < 0.0009). No relationships between biochemical variables and normal levels of TSH were noted in male students. However, surprisingly normal range TSH in males was slightly but significantly correlated with the percentage of body fat and this issue needs further studies concerning measurements of different fat depots. The above data suggests that in active females TG synthesis and export from the liver is more sensitive to TSH action than in active male counterparts.
format	article
author	Marzena Malara Anna Kęska Joanna Tkaczyk Grażyna Lutosławska
author_facet	Marzena Malara Anna Kęska Joanna Tkaczyk Grażyna Lutosławska
author_sort	Marzena Malara
title	Normal Levels of TSH Affect the Metabolic Profile Differently in Physically Active Males and Females
title_short	Normal Levels of TSH Affect the Metabolic Profile Differently in Physically Active Males and Females
title_full	Normal Levels of TSH Affect the Metabolic Profile Differently in Physically Active Males and Females
title_fullStr	Normal Levels of TSH Affect the Metabolic Profile Differently in Physically Active Males and Females
title_full_unstemmed	Normal Levels of TSH Affect the Metabolic Profile Differently in Physically Active Males and Females
title_sort	normal levels of tsh affect the metabolic profile differently in physically active males and females
publisher	Wydawnictwo Naukowe Uniwersytetu Szczecińskiego
publishDate	2021
url	https://doaj.org/article/70afe74d3ee24bc29116f9993dce6669
work_keys_str_mv	AT marzenamalara normallevelsoftshaffectthemetabolicprofiledifferentlyinphysicallyactivemalesandfemales AT annakeska normallevelsoftshaffectthemetabolicprofiledifferentlyinphysicallyactivemalesandfemales AT joannatkaczyk normallevelsoftshaffectthemetabolicprofiledifferentlyinphysicallyactivemalesandfemales AT grazynalutosławska normallevelsoftshaffectthemetabolicprofiledifferentlyinphysicallyactivemalesandfemales
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Normal Levels of TSH Affect the Metabolic Profile Differently in Physically Active Males and Females

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