A new class of rhomboid protease inhibitors discovered by activity-based fluorescence polarization.
Rhomboids are intramembrane serine proteases that play diverse biological roles, including some that are of potential therapeutical relevance. Up to date, rhomboid inhibitor assays are based on protein substrate cleavage. Although rhomboids have an overlapping substrate specificity, substrates canno...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
Public Library of Science (PLoS)
2013
|
| Subjects: | |
| Online Access: | https://doaj.org/article/70b1cebe224a4393822bbb3f7abd2254 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|