TRIM25 contributes to the malignancy of acute myeloid leukemia and is negatively regulated by microRNA-137

Acute myeloid leukemia (AML) is a ubiquitous malignancy that occurs in the hematological system. Tripartite motif-containing 25 (TRIM25) has been found to be involved in various carcinomas comprising AML. However, the function and underlying causative role of TRIM25 in AML are still obscure.

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Autores principales: Wang Sheng, Zhang Bang Shuo, Yang Yi, Li Ying, Lv Jing Long, Cheng Yu
Formato: article
Lenguaje:EN
Publicado: De Gruyter 2020
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R
Acceso en línea:https://doaj.org/article/70bef0e5183848cea927ac7f89c9ff20
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Sumario:Acute myeloid leukemia (AML) is a ubiquitous malignancy that occurs in the hematological system. Tripartite motif-containing 25 (TRIM25) has been found to be involved in various carcinomas comprising AML. However, the function and underlying causative role of TRIM25 in AML are still obscure.