PfCERLI1 is a conserved rhoptry associated protein essential for Plasmodium falciparum merozoite invasion of erythrocytes

Rhoptries are essential organelles for invasion of erythrocytes by Plasmodium. Here, the authors characterize the rhoptry-associated protein CERLI1 using quantitative super-resolution microscopy, showing that it is important for parasite invasion and secretion of rhoptry proteins including vaccine a...

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Autores principales: Benjamin Liffner, Sonja Frölich, Gary K. Heinemann, Boyin Liu, Stuart A. Ralph, Matthew W. A. Dixon, Tim-Wolf Gilberger, Danny W. Wilson
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Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/70c3ecfb941c4e2fb2554ab17a4f110b
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spelling oai:doaj.org-article:70c3ecfb941c4e2fb2554ab17a4f110b2021-12-02T16:56:49ZPfCERLI1 is a conserved rhoptry associated protein essential for Plasmodium falciparum merozoite invasion of erythrocytes10.1038/s41467-020-15127-w2041-1723https://doaj.org/article/70c3ecfb941c4e2fb2554ab17a4f110b2020-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15127-whttps://doaj.org/toc/2041-1723Rhoptries are essential organelles for invasion of erythrocytes by Plasmodium. Here, the authors characterize the rhoptry-associated protein CERLI1 using quantitative super-resolution microscopy, showing that it is important for parasite invasion and secretion of rhoptry proteins including vaccine antigens.Benjamin LiffnerSonja FrölichGary K. HeinemannBoyin LiuStuart A. RalphMatthew W. A. DixonTim-Wolf GilbergerDanny W. WilsonNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Benjamin Liffner
Sonja Frölich
Gary K. Heinemann
Boyin Liu
Stuart A. Ralph
Matthew W. A. Dixon
Tim-Wolf Gilberger
Danny W. Wilson
PfCERLI1 is a conserved rhoptry associated protein essential for Plasmodium falciparum merozoite invasion of erythrocytes
description Rhoptries are essential organelles for invasion of erythrocytes by Plasmodium. Here, the authors characterize the rhoptry-associated protein CERLI1 using quantitative super-resolution microscopy, showing that it is important for parasite invasion and secretion of rhoptry proteins including vaccine antigens.
format article
author Benjamin Liffner
Sonja Frölich
Gary K. Heinemann
Boyin Liu
Stuart A. Ralph
Matthew W. A. Dixon
Tim-Wolf Gilberger
Danny W. Wilson
author_facet Benjamin Liffner
Sonja Frölich
Gary K. Heinemann
Boyin Liu
Stuart A. Ralph
Matthew W. A. Dixon
Tim-Wolf Gilberger
Danny W. Wilson
author_sort Benjamin Liffner
title PfCERLI1 is a conserved rhoptry associated protein essential for Plasmodium falciparum merozoite invasion of erythrocytes
title_short PfCERLI1 is a conserved rhoptry associated protein essential for Plasmodium falciparum merozoite invasion of erythrocytes
title_full PfCERLI1 is a conserved rhoptry associated protein essential for Plasmodium falciparum merozoite invasion of erythrocytes
title_fullStr PfCERLI1 is a conserved rhoptry associated protein essential for Plasmodium falciparum merozoite invasion of erythrocytes
title_full_unstemmed PfCERLI1 is a conserved rhoptry associated protein essential for Plasmodium falciparum merozoite invasion of erythrocytes
title_sort pfcerli1 is a conserved rhoptry associated protein essential for plasmodium falciparum merozoite invasion of erythrocytes
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/70c3ecfb941c4e2fb2554ab17a4f110b
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