PfCERLI1 is a conserved rhoptry associated protein essential for Plasmodium falciparum merozoite invasion of erythrocytes
Rhoptries are essential organelles for invasion of erythrocytes by Plasmodium. Here, the authors characterize the rhoptry-associated protein CERLI1 using quantitative super-resolution microscopy, showing that it is important for parasite invasion and secretion of rhoptry proteins including vaccine a...
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Nature Portfolio
2020
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oai:doaj.org-article:70c3ecfb941c4e2fb2554ab17a4f110b2021-12-02T16:56:49ZPfCERLI1 is a conserved rhoptry associated protein essential for Plasmodium falciparum merozoite invasion of erythrocytes10.1038/s41467-020-15127-w2041-1723https://doaj.org/article/70c3ecfb941c4e2fb2554ab17a4f110b2020-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15127-whttps://doaj.org/toc/2041-1723Rhoptries are essential organelles for invasion of erythrocytes by Plasmodium. Here, the authors characterize the rhoptry-associated protein CERLI1 using quantitative super-resolution microscopy, showing that it is important for parasite invasion and secretion of rhoptry proteins including vaccine antigens.Benjamin LiffnerSonja FrölichGary K. HeinemannBoyin LiuStuart A. RalphMatthew W. A. DixonTim-Wolf GilbergerDanny W. WilsonNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020) |
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Science Q Benjamin Liffner Sonja Frölich Gary K. Heinemann Boyin Liu Stuart A. Ralph Matthew W. A. Dixon Tim-Wolf Gilberger Danny W. Wilson PfCERLI1 is a conserved rhoptry associated protein essential for Plasmodium falciparum merozoite invasion of erythrocytes |
description |
Rhoptries are essential organelles for invasion of erythrocytes by Plasmodium. Here, the authors characterize the rhoptry-associated protein CERLI1 using quantitative super-resolution microscopy, showing that it is important for parasite invasion and secretion of rhoptry proteins including vaccine antigens. |
format |
article |
author |
Benjamin Liffner Sonja Frölich Gary K. Heinemann Boyin Liu Stuart A. Ralph Matthew W. A. Dixon Tim-Wolf Gilberger Danny W. Wilson |
author_facet |
Benjamin Liffner Sonja Frölich Gary K. Heinemann Boyin Liu Stuart A. Ralph Matthew W. A. Dixon Tim-Wolf Gilberger Danny W. Wilson |
author_sort |
Benjamin Liffner |
title |
PfCERLI1 is a conserved rhoptry associated protein essential for Plasmodium falciparum merozoite invasion of erythrocytes |
title_short |
PfCERLI1 is a conserved rhoptry associated protein essential for Plasmodium falciparum merozoite invasion of erythrocytes |
title_full |
PfCERLI1 is a conserved rhoptry associated protein essential for Plasmodium falciparum merozoite invasion of erythrocytes |
title_fullStr |
PfCERLI1 is a conserved rhoptry associated protein essential for Plasmodium falciparum merozoite invasion of erythrocytes |
title_full_unstemmed |
PfCERLI1 is a conserved rhoptry associated protein essential for Plasmodium falciparum merozoite invasion of erythrocytes |
title_sort |
pfcerli1 is a conserved rhoptry associated protein essential for plasmodium falciparum merozoite invasion of erythrocytes |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/70c3ecfb941c4e2fb2554ab17a4f110b |
work_keys_str_mv |
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