Honeybee products for the treatment and recovery from viral respiratory infections including SARS-CoV-2: A rapid systematic review

Background: This rapid review systematically evaluated the effects of honeybee products compared to controls for the prevention, duration, severity, and recovery of acute viral respiratory tract infections (RTIs), including SARS-CoV-2, in adults and children. Methods: Cochrane rapid review methods w...

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Autores principales:	Susan Arentz, Jennifer Hunter, Baljit Khamba, Michelle Mravunac, Zemirah Lee, Kristen Alexander, Romy Lauche, Joshua Goldenberg, Stephen P Myers
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2021
Materias:	Long-COVID COVID-19 Coronavirus pandemic TCIM Complementary medicine Miscellaneous systems and treatments RZ409.7-999
Acceso en línea:	https://doaj.org/article/70c88f53223a4bf09364c8960355b6e8
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spelling	oai:doaj.org-article:70c88f53223a4bf09364c8960355b6e82021-12-04T04:34:08ZHoneybee products for the treatment and recovery from viral respiratory infections including SARS-CoV-2: A rapid systematic review2213-422010.1016/j.imr.2021.100779https://doaj.org/article/70c88f53223a4bf09364c8960355b6e82021-01-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2213422021000664https://doaj.org/toc/2213-4220Background: This rapid review systematically evaluated the effects of honeybee products compared to controls for the prevention, duration, severity, and recovery of acute viral respiratory tract infections (RTIs), including SARS-CoV-2, in adults and children. Methods: Cochrane rapid review methods were applied. Four English databases plus preprint servers and trial registries were searched for randomized controlled trials (RCTs). The evidence was appraised and synthesized using RoB 2.0 and GRADE. Results: 27 results were derived from 9 RCTs that included 674 adults and 781 children. In hospitalized adults with SARS-CoV-2, propolis plus usual-care compared to usual-care alone reduced the risk of shock, respiratory failure and kidney injury and duration of hospital admission. Honey was less effective than Guaifenesin for reducing cough severity at 60-minutes in adults with non-specific acute viral RTIs. Compared to coffee, honey plus coffee, and honey alone reduced the severity of post-infectious cough in adults. Honey reduced the duration of cough in children compared to placebo and salbutamol; and the global impact of nocturnal cough after one night compared to usual-care alone and pharmaceutical cough medicines. Conclusion: More studies are needed to robustly assess honeybee's role in SARS-CoV-2 and non-specific viral respiratory infections. Protocol registration: PROSPERO: CRD42020193847.Susan ArentzJennifer HunterBaljit KhambaMichelle MravunacZemirah LeeKristen AlexanderRomy LaucheJoshua GoldenbergStephen P MyersElsevierarticleLong-COVIDCOVID-19Coronavirus pandemicTCIMComplementary medicineMiscellaneous systems and treatmentsRZ409.7-999ENIntegrative Medicine Research, Vol 10, Iss , Pp 100779- (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Long-COVID COVID-19 Coronavirus pandemic TCIM Complementary medicine Miscellaneous systems and treatments RZ409.7-999
spellingShingle	Long-COVID COVID-19 Coronavirus pandemic TCIM Complementary medicine Miscellaneous systems and treatments RZ409.7-999 Susan Arentz Jennifer Hunter Baljit Khamba Michelle Mravunac Zemirah Lee Kristen Alexander Romy Lauche Joshua Goldenberg Stephen P Myers Honeybee products for the treatment and recovery from viral respiratory infections including SARS-CoV-2: A rapid systematic review
description	Background: This rapid review systematically evaluated the effects of honeybee products compared to controls for the prevention, duration, severity, and recovery of acute viral respiratory tract infections (RTIs), including SARS-CoV-2, in adults and children. Methods: Cochrane rapid review methods were applied. Four English databases plus preprint servers and trial registries were searched for randomized controlled trials (RCTs). The evidence was appraised and synthesized using RoB 2.0 and GRADE. Results: 27 results were derived from 9 RCTs that included 674 adults and 781 children. In hospitalized adults with SARS-CoV-2, propolis plus usual-care compared to usual-care alone reduced the risk of shock, respiratory failure and kidney injury and duration of hospital admission. Honey was less effective than Guaifenesin for reducing cough severity at 60-minutes in adults with non-specific acute viral RTIs. Compared to coffee, honey plus coffee, and honey alone reduced the severity of post-infectious cough in adults. Honey reduced the duration of cough in children compared to placebo and salbutamol; and the global impact of nocturnal cough after one night compared to usual-care alone and pharmaceutical cough medicines. Conclusion: More studies are needed to robustly assess honeybee's role in SARS-CoV-2 and non-specific viral respiratory infections. Protocol registration: PROSPERO: CRD42020193847.
format	article
author	Susan Arentz Jennifer Hunter Baljit Khamba Michelle Mravunac Zemirah Lee Kristen Alexander Romy Lauche Joshua Goldenberg Stephen P Myers
author_facet	Susan Arentz Jennifer Hunter Baljit Khamba Michelle Mravunac Zemirah Lee Kristen Alexander Romy Lauche Joshua Goldenberg Stephen P Myers
author_sort	Susan Arentz
title	Honeybee products for the treatment and recovery from viral respiratory infections including SARS-CoV-2: A rapid systematic review
title_short	Honeybee products for the treatment and recovery from viral respiratory infections including SARS-CoV-2: A rapid systematic review
title_full	Honeybee products for the treatment and recovery from viral respiratory infections including SARS-CoV-2: A rapid systematic review
title_fullStr	Honeybee products for the treatment and recovery from viral respiratory infections including SARS-CoV-2: A rapid systematic review
title_full_unstemmed	Honeybee products for the treatment and recovery from viral respiratory infections including SARS-CoV-2: A rapid systematic review
title_sort	honeybee products for the treatment and recovery from viral respiratory infections including sars-cov-2: a rapid systematic review
publisher	Elsevier
publishDate	2021
url	https://doaj.org/article/70c88f53223a4bf09364c8960355b6e8
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Honeybee products for the treatment and recovery from viral respiratory infections including SARS-CoV-2: A rapid systematic review

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