Aurora A drives early signalling and vesicle dynamics during T-cell activation

Aurora A is a protein kinase that contributes to the progression of mitosis by stimulating microtubule nucleation. Here the authors show that Aurora A also functions during T cell activation by maintaining TCR signaling through Lck activation.

Guardado en:

Detalles Bibliográficos
Autores principales:	Noelia Blas-Rus, Eugenio Bustos-Morán, Ignacio Pérez de Castro, Guillermo de Cárcer, Aldo Borroto, Emilio Camafeita, Inmaculada Jorge, Jesús Vázquez, Balbino Alarcón, Marcos Malumbres, Noa B. Martín-Cófreces, Francisco Sánchez-Madrid
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/70cde4b8e22c4dcfa69bb2d3c104caa9
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:70cde4b8e22c4dcfa69bb2d3c104caa9
record_format	dspace
spelling	oai:doaj.org-article:70cde4b8e22c4dcfa69bb2d3c104caa92021-12-02T14:39:30ZAurora A drives early signalling and vesicle dynamics during T-cell activation10.1038/ncomms113892041-1723https://doaj.org/article/70cde4b8e22c4dcfa69bb2d3c104caa92016-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms11389https://doaj.org/toc/2041-1723Aurora A is a protein kinase that contributes to the progression of mitosis by stimulating microtubule nucleation. Here the authors show that Aurora A also functions during T cell activation by maintaining TCR signaling through Lck activation.Noelia Blas-RusEugenio Bustos-MoránIgnacio Pérez de CastroGuillermo de CárcerAldo BorrotoEmilio CamafeitaInmaculada JorgeJesús VázquezBalbino AlarcónMarcos MalumbresNoa B. Martín-CófrecesFrancisco Sánchez-MadridNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-16 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Noelia Blas-Rus Eugenio Bustos-Morán Ignacio Pérez de Castro Guillermo de Cárcer Aldo Borroto Emilio Camafeita Inmaculada Jorge Jesús Vázquez Balbino Alarcón Marcos Malumbres Noa B. Martín-Cófreces Francisco Sánchez-Madrid Aurora A drives early signalling and vesicle dynamics during T-cell activation
description	Aurora A is a protein kinase that contributes to the progression of mitosis by stimulating microtubule nucleation. Here the authors show that Aurora A also functions during T cell activation by maintaining TCR signaling through Lck activation.
format	article
author	Noelia Blas-Rus Eugenio Bustos-Morán Ignacio Pérez de Castro Guillermo de Cárcer Aldo Borroto Emilio Camafeita Inmaculada Jorge Jesús Vázquez Balbino Alarcón Marcos Malumbres Noa B. Martín-Cófreces Francisco Sánchez-Madrid
author_facet	Noelia Blas-Rus Eugenio Bustos-Morán Ignacio Pérez de Castro Guillermo de Cárcer Aldo Borroto Emilio Camafeita Inmaculada Jorge Jesús Vázquez Balbino Alarcón Marcos Malumbres Noa B. Martín-Cófreces Francisco Sánchez-Madrid
author_sort	Noelia Blas-Rus
title	Aurora A drives early signalling and vesicle dynamics during T-cell activation
title_short	Aurora A drives early signalling and vesicle dynamics during T-cell activation
title_full	Aurora A drives early signalling and vesicle dynamics during T-cell activation
title_fullStr	Aurora A drives early signalling and vesicle dynamics during T-cell activation
title_full_unstemmed	Aurora A drives early signalling and vesicle dynamics during T-cell activation
title_sort	aurora a drives early signalling and vesicle dynamics during t-cell activation
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/70cde4b8e22c4dcfa69bb2d3c104caa9
work_keys_str_mv	AT noeliablasrus auroraadrivesearlysignallingandvesicledynamicsduringtcellactivation AT eugeniobustosmoran auroraadrivesearlysignallingandvesicledynamicsduringtcellactivation AT ignacioperezdecastro auroraadrivesearlysignallingandvesicledynamicsduringtcellactivation AT guillermodecarcer auroraadrivesearlysignallingandvesicledynamicsduringtcellactivation AT aldoborroto auroraadrivesearlysignallingandvesicledynamicsduringtcellactivation AT emiliocamafeita auroraadrivesearlysignallingandvesicledynamicsduringtcellactivation AT inmaculadajorge auroraadrivesearlysignallingandvesicledynamicsduringtcellactivation AT jesusvazquez auroraadrivesearlysignallingandvesicledynamicsduringtcellactivation AT balbinoalarcon auroraadrivesearlysignallingandvesicledynamicsduringtcellactivation AT marcosmalumbres auroraadrivesearlysignallingandvesicledynamicsduringtcellactivation AT noabmartincofreces auroraadrivesearlysignallingandvesicledynamicsduringtcellactivation AT franciscosanchezmadrid auroraadrivesearlysignallingandvesicledynamicsduringtcellactivation
_version_	1718390598534168576

Aurora A drives early signalling and vesicle dynamics during T-cell activation

Ejemplares similares