Origin Replication Complex Binding, Nucleosome Depletion Patterns, and a Primary Sequence Motif Can Predict Origins of Replication in a Genome with Epigenetic Centromeres

ABSTRACT Origins of DNA replication are key genetic elements, yet their identification remains elusive in most organisms. In previous work, we found that centromeres contain origins of replication (ORIs) that are determined epigenetically in the pathogenic yeast Candida albicans. In this study, we u...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Hung-Ji Tsai, Joshua A. Baller, Ivan Liachko, Amnon Koren, Laura S. Burrack, Meleah A. Hickman, Mathuravani A. Thevandavakkam, Laura N. Rusche, Judith Berman
Format: article
Langue:EN
Publié: American Society for Microbiology 2014
Sujets:
Accès en ligne:https://doaj.org/article/70e68d4e98f34ef9b64f1dcf46320fb4
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!