Alkyladenine DNA glycosylase associates with transcription elongation to coordinate DNA repair with gene expression

Alkyladenine DNA glycosylase associates with transcription elongation to coordinate DNA repair with gene expression

How genome stability is maintained at regions of active transcription is currently not entirely clear. Here, the authors reveal an association between base excision repair factors and transcription elongation to modulate DNA repair.

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Bibliographic Details
Main Authors: Nicola P. Montaldo, Diana L. Bordin, Alessandro Brambilla, Marcel Rösinger, Sarah L. Fordyce Martin, Karine Øian Bjørås, Stefano Bradamante, Per Arne Aas, Antonia Furrer, Lene C. Olsen, Nicolas Kunath, Marit Otterlei, Pål Sætrom, Magnar Bjørås, Leona D. Samson, Barbara van Loon
Format: article
Language:EN
Published: Nature Portfolio 2019
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Science
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Online Access:https://doaj.org/article/70eb1296de944cc58fe067e2201fa6bb
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Summary:How genome stability is maintained at regions of active transcription is currently not entirely clear. Here, the authors reveal an association between base excision repair factors and transcription elongation to modulate DNA repair.

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