Early oral tongue cancer initially managed with surgery alone: Treatment of recurrence

Objective: To report T1-2N0 tongue cancer recurrences initially treated with surgery alone. Methods: Between 1990 and 2010, 27 patients at tertiary hospital referral center institution were treated with curative intent for locoregional recurrence after initial glossectomy with or without neck dissec...

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Autores principales:	Jeffrey C. Liu, Dennis S. Sopka, Ranee Mehra, Miriam N. Lango, Christopher Fundakowski, John A. Ridge, Thomas J. Galloway
Formato:	article
Lenguaje:	EN
Publicado:	KeAi Communications Co., Ltd. 2016
Materias:	Otorhinolaryngology RF1-547 Surgery RD1-811
Acceso en línea:	https://doaj.org/article/70eb55775336410bbc60a1882083bf5b
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spelling	oai:doaj.org-article:70eb55775336410bbc60a1882083bf5b2021-12-02T14:11:40ZEarly oral tongue cancer initially managed with surgery alone: Treatment of recurrence2095-881110.1016/j.wjorl.2016.03.001https://doaj.org/article/70eb55775336410bbc60a1882083bf5b2016-12-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2095881116300026https://doaj.org/toc/2095-8811Objective: To report T1-2N0 tongue cancer recurrences initially treated with surgery alone. Methods: Between 1990 and 2010, 27 patients at tertiary hospital referral center institution were treated with curative intent for locoregional recurrence after initial glossectomy with or without neck dissection for T1-2N0 tongue cancer. None had received adjuvant postoperative radiation as a component of the original treatment. Results: Median time to locoregional recurrence was 12 months (range 5â39 months) and 78% of failures occurred in the first 2 years. Most treatment failures were local (63%). Salvage strategy was risk-adapted by individual patient. The 5-year disease specific survival (DSS) was 61%. Patients with local recurrences alone fared significantly better than those with regional recurrences (5-yr DSS: 86% vs. 22%, PÂ =Â 0.0018). Local recurrences were usually treated by surgery alone, while regional recurrences were more commonly treated with combined modality treatment (PÂ =Â 0.005). Conclusions: Recurrence of early stage oral tongue cancer can be successfully salvaged in a majority of cases. Patients developing regional recurrence have significantly worse prognosis than those with local failures. Keywords: Oral cancer, Head and neck cancer, Tongue neoplasms, Salvage therapyJeffrey C. LiuDennis S. SopkaRanee MehraMiriam N. LangoChristopher FundakowskiJohn A. RidgeThomas J. GallowayKeAi Communications Co., Ltd.articleOtorhinolaryngologyRF1-547SurgeryRD1-811ENWorld Journal of Otorhinolaryngology-Head and Neck Surgery, Vol 2, Iss 4, Pp 193-197 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Otorhinolaryngology RF1-547 Surgery RD1-811
spellingShingle	Otorhinolaryngology RF1-547 Surgery RD1-811 Jeffrey C. Liu Dennis S. Sopka Ranee Mehra Miriam N. Lango Christopher Fundakowski John A. Ridge Thomas J. Galloway Early oral tongue cancer initially managed with surgery alone: Treatment of recurrence
description	Objective: To report T1-2N0 tongue cancer recurrences initially treated with surgery alone. Methods: Between 1990 and 2010, 27 patients at tertiary hospital referral center institution were treated with curative intent for locoregional recurrence after initial glossectomy with or without neck dissection for T1-2N0 tongue cancer. None had received adjuvant postoperative radiation as a component of the original treatment. Results: Median time to locoregional recurrence was 12 months (range 5â39 months) and 78% of failures occurred in the first 2 years. Most treatment failures were local (63%). Salvage strategy was risk-adapted by individual patient. The 5-year disease specific survival (DSS) was 61%. Patients with local recurrences alone fared significantly better than those with regional recurrences (5-yr DSS: 86% vs. 22%, PÂ =Â 0.0018). Local recurrences were usually treated by surgery alone, while regional recurrences were more commonly treated with combined modality treatment (PÂ =Â 0.005). Conclusions: Recurrence of early stage oral tongue cancer can be successfully salvaged in a majority of cases. Patients developing regional recurrence have significantly worse prognosis than those with local failures. Keywords: Oral cancer, Head and neck cancer, Tongue neoplasms, Salvage therapy
format	article
author	Jeffrey C. Liu Dennis S. Sopka Ranee Mehra Miriam N. Lango Christopher Fundakowski John A. Ridge Thomas J. Galloway
author_facet	Jeffrey C. Liu Dennis S. Sopka Ranee Mehra Miriam N. Lango Christopher Fundakowski John A. Ridge Thomas J. Galloway
author_sort	Jeffrey C. Liu
title	Early oral tongue cancer initially managed with surgery alone: Treatment of recurrence
title_short	Early oral tongue cancer initially managed with surgery alone: Treatment of recurrence
title_full	Early oral tongue cancer initially managed with surgery alone: Treatment of recurrence
title_fullStr	Early oral tongue cancer initially managed with surgery alone: Treatment of recurrence
title_full_unstemmed	Early oral tongue cancer initially managed with surgery alone: Treatment of recurrence
title_sort	early oral tongue cancer initially managed with surgery alone: treatment of recurrence
publisher	KeAi Communications Co., Ltd.
publishDate	2016
url	https://doaj.org/article/70eb55775336410bbc60a1882083bf5b
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Early oral tongue cancer initially managed with surgery alone: Treatment of recurrence

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