Targeting SARS-CoV-2 receptor-binding domain to cells expressing CD40 improves protection to infection in convalescent macaques

In this study, Marlin et al. provide insights into the potential use of subunit vaccines that induce a high level of protection against SARS-CoV-2 in animal models.

Guardado en:
Detalles Bibliográficos
Autores principales: Romain Marlin, Veronique Godot, Sylvain Cardinaud, Mathilde Galhaut, Severin Coleon, Sandra Zurawski, Nathalie Dereuddre-Bosquet, Mariangela Cavarelli, Anne-Sophie Gallouët, Pauline Maisonnasse, Léa Dupaty, Craig Fenwick, Thibaut Naninck, Julien Lemaitre, Mario Gomez-Pacheco, Nidhal Kahlaoui, Vanessa Contreras, Francis Relouzat, Raphaël Ho Tsong Fang, Zhiqing Wang, Jerome Ellis, Catherine Chapon, Mireille Centlivre, Aurelie Wiedemann, Christine Lacabaratz, Mathieu Surenaud, Inga Szurgot, Peter Liljeström, Delphine Planas, Timothée Bruel, Olivier Schwartz, Sylvie van der Werf, Giuseppe Pantaleo, Mélanie Prague, Rodolphe Thiébaut, Gerard Zurawski, Yves Lévy, Roger Le Grand
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Q
Acceso en línea:https://doaj.org/article/70f82fe99a894f91b058c7b831c415e2
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:70f82fe99a894f91b058c7b831c415e2
record_format dspace
spelling oai:doaj.org-article:70f82fe99a894f91b058c7b831c415e22021-12-02T15:25:36ZTargeting SARS-CoV-2 receptor-binding domain to cells expressing CD40 improves protection to infection in convalescent macaques10.1038/s41467-021-25382-02041-1723https://doaj.org/article/70f82fe99a894f91b058c7b831c415e22021-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25382-0https://doaj.org/toc/2041-1723In this study, Marlin et al. provide insights into the potential use of subunit vaccines that induce a high level of protection against SARS-CoV-2 in animal models.Romain MarlinVeronique GodotSylvain CardinaudMathilde GalhautSeverin ColeonSandra ZurawskiNathalie Dereuddre-BosquetMariangela CavarelliAnne-Sophie GallouëtPauline MaisonnasseLéa DupatyCraig FenwickThibaut NaninckJulien LemaitreMario Gomez-PachecoNidhal KahlaouiVanessa ContrerasFrancis RelouzatRaphaël Ho Tsong FangZhiqing WangJerome EllisCatherine ChaponMireille CentlivreAurelie WiedemannChristine LacabaratzMathieu SurenaudInga SzurgotPeter LiljeströmDelphine PlanasTimothée BruelOlivier SchwartzSylvie van der WerfGiuseppe PantaleoMélanie PragueRodolphe ThiébautGerard ZurawskiYves LévyRoger Le GrandNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Romain Marlin
Veronique Godot
Sylvain Cardinaud
Mathilde Galhaut
Severin Coleon
Sandra Zurawski
Nathalie Dereuddre-Bosquet
Mariangela Cavarelli
Anne-Sophie Gallouët
Pauline Maisonnasse
Léa Dupaty
Craig Fenwick
Thibaut Naninck
Julien Lemaitre
Mario Gomez-Pacheco
Nidhal Kahlaoui
Vanessa Contreras
Francis Relouzat
Raphaël Ho Tsong Fang
Zhiqing Wang
Jerome Ellis
Catherine Chapon
Mireille Centlivre
Aurelie Wiedemann
Christine Lacabaratz
Mathieu Surenaud
Inga Szurgot
Peter Liljeström
Delphine Planas
Timothée Bruel
Olivier Schwartz
Sylvie van der Werf
Giuseppe Pantaleo
Mélanie Prague
Rodolphe Thiébaut
Gerard Zurawski
Yves Lévy
Roger Le Grand
Targeting SARS-CoV-2 receptor-binding domain to cells expressing CD40 improves protection to infection in convalescent macaques
description In this study, Marlin et al. provide insights into the potential use of subunit vaccines that induce a high level of protection against SARS-CoV-2 in animal models.
format article
author Romain Marlin
Veronique Godot
Sylvain Cardinaud
Mathilde Galhaut
Severin Coleon
Sandra Zurawski
Nathalie Dereuddre-Bosquet
Mariangela Cavarelli
Anne-Sophie Gallouët
Pauline Maisonnasse
Léa Dupaty
Craig Fenwick
Thibaut Naninck
Julien Lemaitre
Mario Gomez-Pacheco
Nidhal Kahlaoui
Vanessa Contreras
Francis Relouzat
Raphaël Ho Tsong Fang
Zhiqing Wang
Jerome Ellis
Catherine Chapon
Mireille Centlivre
Aurelie Wiedemann
Christine Lacabaratz
Mathieu Surenaud
Inga Szurgot
Peter Liljeström
Delphine Planas
Timothée Bruel
Olivier Schwartz
Sylvie van der Werf
Giuseppe Pantaleo
Mélanie Prague
Rodolphe Thiébaut
Gerard Zurawski
Yves Lévy
Roger Le Grand
author_facet Romain Marlin
Veronique Godot
Sylvain Cardinaud
Mathilde Galhaut
Severin Coleon
Sandra Zurawski
Nathalie Dereuddre-Bosquet
Mariangela Cavarelli
Anne-Sophie Gallouët
Pauline Maisonnasse
Léa Dupaty
Craig Fenwick
Thibaut Naninck
Julien Lemaitre
Mario Gomez-Pacheco
Nidhal Kahlaoui
Vanessa Contreras
Francis Relouzat
Raphaël Ho Tsong Fang
Zhiqing Wang
Jerome Ellis
Catherine Chapon
Mireille Centlivre
Aurelie Wiedemann
Christine Lacabaratz
Mathieu Surenaud
Inga Szurgot
Peter Liljeström
Delphine Planas
Timothée Bruel
Olivier Schwartz
Sylvie van der Werf
Giuseppe Pantaleo
Mélanie Prague
Rodolphe Thiébaut
Gerard Zurawski
Yves Lévy
Roger Le Grand
author_sort Romain Marlin
title Targeting SARS-CoV-2 receptor-binding domain to cells expressing CD40 improves protection to infection in convalescent macaques
title_short Targeting SARS-CoV-2 receptor-binding domain to cells expressing CD40 improves protection to infection in convalescent macaques
title_full Targeting SARS-CoV-2 receptor-binding domain to cells expressing CD40 improves protection to infection in convalescent macaques
title_fullStr Targeting SARS-CoV-2 receptor-binding domain to cells expressing CD40 improves protection to infection in convalescent macaques
title_full_unstemmed Targeting SARS-CoV-2 receptor-binding domain to cells expressing CD40 improves protection to infection in convalescent macaques
title_sort targeting sars-cov-2 receptor-binding domain to cells expressing cd40 improves protection to infection in convalescent macaques
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/70f82fe99a894f91b058c7b831c415e2
work_keys_str_mv AT romainmarlin targetingsarscov2receptorbindingdomaintocellsexpressingcd40improvesprotectiontoinfectioninconvalescentmacaques
AT veroniquegodot targetingsarscov2receptorbindingdomaintocellsexpressingcd40improvesprotectiontoinfectioninconvalescentmacaques
AT sylvaincardinaud targetingsarscov2receptorbindingdomaintocellsexpressingcd40improvesprotectiontoinfectioninconvalescentmacaques
AT mathildegalhaut targetingsarscov2receptorbindingdomaintocellsexpressingcd40improvesprotectiontoinfectioninconvalescentmacaques
AT severincoleon targetingsarscov2receptorbindingdomaintocellsexpressingcd40improvesprotectiontoinfectioninconvalescentmacaques
AT sandrazurawski targetingsarscov2receptorbindingdomaintocellsexpressingcd40improvesprotectiontoinfectioninconvalescentmacaques
AT nathaliedereuddrebosquet targetingsarscov2receptorbindingdomaintocellsexpressingcd40improvesprotectiontoinfectioninconvalescentmacaques
AT mariangelacavarelli targetingsarscov2receptorbindingdomaintocellsexpressingcd40improvesprotectiontoinfectioninconvalescentmacaques
AT annesophiegallouet targetingsarscov2receptorbindingdomaintocellsexpressingcd40improvesprotectiontoinfectioninconvalescentmacaques
AT paulinemaisonnasse targetingsarscov2receptorbindingdomaintocellsexpressingcd40improvesprotectiontoinfectioninconvalescentmacaques
AT leadupaty targetingsarscov2receptorbindingdomaintocellsexpressingcd40improvesprotectiontoinfectioninconvalescentmacaques
AT craigfenwick targetingsarscov2receptorbindingdomaintocellsexpressingcd40improvesprotectiontoinfectioninconvalescentmacaques
AT thibautnaninck targetingsarscov2receptorbindingdomaintocellsexpressingcd40improvesprotectiontoinfectioninconvalescentmacaques
AT julienlemaitre targetingsarscov2receptorbindingdomaintocellsexpressingcd40improvesprotectiontoinfectioninconvalescentmacaques
AT mariogomezpacheco targetingsarscov2receptorbindingdomaintocellsexpressingcd40improvesprotectiontoinfectioninconvalescentmacaques
AT nidhalkahlaoui targetingsarscov2receptorbindingdomaintocellsexpressingcd40improvesprotectiontoinfectioninconvalescentmacaques
AT vanessacontreras targetingsarscov2receptorbindingdomaintocellsexpressingcd40improvesprotectiontoinfectioninconvalescentmacaques
AT francisrelouzat targetingsarscov2receptorbindingdomaintocellsexpressingcd40improvesprotectiontoinfectioninconvalescentmacaques
AT raphaelhotsongfang targetingsarscov2receptorbindingdomaintocellsexpressingcd40improvesprotectiontoinfectioninconvalescentmacaques
AT zhiqingwang targetingsarscov2receptorbindingdomaintocellsexpressingcd40improvesprotectiontoinfectioninconvalescentmacaques
AT jeromeellis targetingsarscov2receptorbindingdomaintocellsexpressingcd40improvesprotectiontoinfectioninconvalescentmacaques
AT catherinechapon targetingsarscov2receptorbindingdomaintocellsexpressingcd40improvesprotectiontoinfectioninconvalescentmacaques
AT mireillecentlivre targetingsarscov2receptorbindingdomaintocellsexpressingcd40improvesprotectiontoinfectioninconvalescentmacaques
AT aureliewiedemann targetingsarscov2receptorbindingdomaintocellsexpressingcd40improvesprotectiontoinfectioninconvalescentmacaques
AT christinelacabaratz targetingsarscov2receptorbindingdomaintocellsexpressingcd40improvesprotectiontoinfectioninconvalescentmacaques
AT mathieusurenaud targetingsarscov2receptorbindingdomaintocellsexpressingcd40improvesprotectiontoinfectioninconvalescentmacaques
AT ingaszurgot targetingsarscov2receptorbindingdomaintocellsexpressingcd40improvesprotectiontoinfectioninconvalescentmacaques
AT peterliljestrom targetingsarscov2receptorbindingdomaintocellsexpressingcd40improvesprotectiontoinfectioninconvalescentmacaques
AT delphineplanas targetingsarscov2receptorbindingdomaintocellsexpressingcd40improvesprotectiontoinfectioninconvalescentmacaques
AT timotheebruel targetingsarscov2receptorbindingdomaintocellsexpressingcd40improvesprotectiontoinfectioninconvalescentmacaques
AT olivierschwartz targetingsarscov2receptorbindingdomaintocellsexpressingcd40improvesprotectiontoinfectioninconvalescentmacaques
AT sylvievanderwerf targetingsarscov2receptorbindingdomaintocellsexpressingcd40improvesprotectiontoinfectioninconvalescentmacaques
AT giuseppepantaleo targetingsarscov2receptorbindingdomaintocellsexpressingcd40improvesprotectiontoinfectioninconvalescentmacaques
AT melanieprague targetingsarscov2receptorbindingdomaintocellsexpressingcd40improvesprotectiontoinfectioninconvalescentmacaques
AT rodolphethiebaut targetingsarscov2receptorbindingdomaintocellsexpressingcd40improvesprotectiontoinfectioninconvalescentmacaques
AT gerardzurawski targetingsarscov2receptorbindingdomaintocellsexpressingcd40improvesprotectiontoinfectioninconvalescentmacaques
AT yveslevy targetingsarscov2receptorbindingdomaintocellsexpressingcd40improvesprotectiontoinfectioninconvalescentmacaques
AT rogerlegrand targetingsarscov2receptorbindingdomaintocellsexpressingcd40improvesprotectiontoinfectioninconvalescentmacaques
_version_ 1718387209138077696