Incidence and Risk Factors of Nosocomial Bloodstream Infections in Pediatric Intensive Care Unit

Introduction:Nosocomial bloodstream infection (BSI) is an important problem in pediatric intensive care unit (PICU) due to high mortality rates, increased hospitalization and costs. We aimed to define the risk factors, incidence and the microorganisms of BSI in PICU in the present study.Methods:The...

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Autores principales:	Fatma Akgül, Gazi Arslan, Ünal Utku Karaarslan, Murat Duman, Tolga Fikri Köroğlu
Formato:	article
Lenguaje:	EN TR
Publicado:	Galenos Yayinevi 2021
Materias:	nosocomial infection bloodstream infection sepsis Medicine R Pediatrics RJ1-570 Medical emergencies. Critical care. Intensive care. First aid RC86-88.9
Acceso en línea:	https://doaj.org/article/70fae6620fcf40cbbdab857fef7b481f
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spelling	oai:doaj.org-article:70fae6620fcf40cbbdab857fef7b481f2021-11-23T10:20:16ZIncidence and Risk Factors of Nosocomial Bloodstream Infections in Pediatric Intensive Care Unit2146-23992148-733210.4274/cayd.galenos.2021.81994https://doaj.org/article/70fae6620fcf40cbbdab857fef7b481f2021-12-01T00:00:00Z http://www.caybdergi.com/archives/archive-detail/article-preview/ncidence-and-risk-factors-of-nosocomial-bloodstrea/49678 https://doaj.org/toc/2146-2399https://doaj.org/toc/2148-7332Introduction:Nosocomial bloodstream infection (BSI) is an important problem in pediatric intensive care unit (PICU) due to high mortality rates, increased hospitalization and costs. We aimed to define the risk factors, incidence and the microorganisms of BSI in PICU in the present study.Methods:The patients admitted to Dokuz Eylül University PICU between January 2011 and January 2013 and stayed in hospital more than 48 hours were evaluated. The patients who had nosocomial BSI were determined and compared with the patients who did not have nosocomial infection during their hospitalization in terms of demographic data, hospitalization diagnoses and underlying chronic diseases, and the treatments applied. Microorganisms isolated in blood culture were also recorded.Results:Two hundred fifty two patients were admitted to the study and fifty-eight BSI episodes developed, 55% of population were male (M/F: 1.2) and the median of age was 10 months. The incidence rate of bloodstream infection was 14.7 per 1.000 patient-days. The median duration in PICU for development of BSI was 16.5 days. Nosocomial BSI was more common in patients with central venous catheter, mechanical ventilation, use of steroid treatments. In the presence of congenital heart disease, metabolic disease, neurological disease or genetic syndrome, the frequency of nosocomial BSI was increased. Risk factors for nosocomial BSI were genetic syndrome and longer hospitalization in PICU. The most common isolated agents were coagulase-negative Staphylococcus (48%), Klebsiella spp. (24%), Enterobacter spp. (9%) and Candida spp. (9%).Conclusion:It is important to know the risk factors for BSIs and taking precautions in this direction is particularly important in terms of reducing treatment costs and mortality. Since the risk increases as the number of days spent in intensive care increases, the length of stay should be kept as short as possible.Fatma AkgülGazi ArslanÜnal Utku KaraarslanMurat DumanTolga Fikri KöroğluGalenos Yayineviarticlenosocomial infectionbloodstream infectionsepsisMedicineRPediatricsRJ1-570Medical emergencies. Critical care. Intensive care. First aidRC86-88.9ENTRJournal of Pediatric Emergency and Intensive Care Medicine, Vol 8, Iss 3, Pp 159-165 (2021)
institution	DOAJ
collection	DOAJ
language	EN TR
topic	nosocomial infection bloodstream infection sepsis Medicine R Pediatrics RJ1-570 Medical emergencies. Critical care. Intensive care. First aid RC86-88.9
spellingShingle	nosocomial infection bloodstream infection sepsis Medicine R Pediatrics RJ1-570 Medical emergencies. Critical care. Intensive care. First aid RC86-88.9 Fatma Akgül Gazi Arslan Ünal Utku Karaarslan Murat Duman Tolga Fikri Köroğlu Incidence and Risk Factors of Nosocomial Bloodstream Infections in Pediatric Intensive Care Unit
description	Introduction:Nosocomial bloodstream infection (BSI) is an important problem in pediatric intensive care unit (PICU) due to high mortality rates, increased hospitalization and costs. We aimed to define the risk factors, incidence and the microorganisms of BSI in PICU in the present study.Methods:The patients admitted to Dokuz Eylül University PICU between January 2011 and January 2013 and stayed in hospital more than 48 hours were evaluated. The patients who had nosocomial BSI were determined and compared with the patients who did not have nosocomial infection during their hospitalization in terms of demographic data, hospitalization diagnoses and underlying chronic diseases, and the treatments applied. Microorganisms isolated in blood culture were also recorded.Results:Two hundred fifty two patients were admitted to the study and fifty-eight BSI episodes developed, 55% of population were male (M/F: 1.2) and the median of age was 10 months. The incidence rate of bloodstream infection was 14.7 per 1.000 patient-days. The median duration in PICU for development of BSI was 16.5 days. Nosocomial BSI was more common in patients with central venous catheter, mechanical ventilation, use of steroid treatments. In the presence of congenital heart disease, metabolic disease, neurological disease or genetic syndrome, the frequency of nosocomial BSI was increased. Risk factors for nosocomial BSI were genetic syndrome and longer hospitalization in PICU. The most common isolated agents were coagulase-negative Staphylococcus (48%), Klebsiella spp. (24%), Enterobacter spp. (9%) and Candida spp. (9%).Conclusion:It is important to know the risk factors for BSIs and taking precautions in this direction is particularly important in terms of reducing treatment costs and mortality. Since the risk increases as the number of days spent in intensive care increases, the length of stay should be kept as short as possible.
format	article
author	Fatma Akgül Gazi Arslan Ünal Utku Karaarslan Murat Duman Tolga Fikri Köroğlu
author_facet	Fatma Akgül Gazi Arslan Ünal Utku Karaarslan Murat Duman Tolga Fikri Köroğlu
author_sort	Fatma Akgül
title	Incidence and Risk Factors of Nosocomial Bloodstream Infections in Pediatric Intensive Care Unit
title_short	Incidence and Risk Factors of Nosocomial Bloodstream Infections in Pediatric Intensive Care Unit
title_full	Incidence and Risk Factors of Nosocomial Bloodstream Infections in Pediatric Intensive Care Unit
title_fullStr	Incidence and Risk Factors of Nosocomial Bloodstream Infections in Pediatric Intensive Care Unit
title_full_unstemmed	Incidence and Risk Factors of Nosocomial Bloodstream Infections in Pediatric Intensive Care Unit
title_sort	incidence and risk factors of nosocomial bloodstream infections in pediatric intensive care unit
publisher	Galenos Yayinevi
publishDate	2021
url	https://doaj.org/article/70fae6620fcf40cbbdab857fef7b481f
work_keys_str_mv	AT fatmaakgul incidenceandriskfactorsofnosocomialbloodstreaminfectionsinpediatricintensivecareunit AT gaziarslan incidenceandriskfactorsofnosocomialbloodstreaminfectionsinpediatricintensivecareunit AT unalutkukaraarslan incidenceandriskfactorsofnosocomialbloodstreaminfectionsinpediatricintensivecareunit AT muratduman incidenceandriskfactorsofnosocomialbloodstreaminfectionsinpediatricintensivecareunit AT tolgafikrikoroglu incidenceandriskfactorsofnosocomialbloodstreaminfectionsinpediatricintensivecareunit
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Incidence and Risk Factors of Nosocomial Bloodstream Infections in Pediatric Intensive Care Unit

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