An asymmetric post-hydrolysis state of the ABC transporter ATPase dimer.

ABC transporters are a superfamily of enzyme pumps that hydrolyse ATP in exchange for translocation of substrates across cellular membranes. Architecturally, ABC transporters are a dimer of transmembrane domains coupled to a dimer of nucleotide binding domains (NBDs): the NBD dimer contains two ATP-...

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Autores principales: Anthony M George, Peter M Jones
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/70fc80223f184c9c8315385378ff8822
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