Central and peripheral control of food intake

The maintenance of the body weight at a stable level is a major determinant in keeping the higher animals and mammals survive. Th e body weight depends on the balance between the energy intake and energy expenditure. Increased food intake over the energy expenditure of prolonged time period results...

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Autor principal:	Abdalla M. M. I.
Formato:	article
Lenguaje:	EN
Publicado:	Sciendo 2017
Materias:	food intake gastrointestinal hormones energy balance satiety signals adiposity signals Diseases of the endocrine glands. Clinical endocrinology RC648-665
Acceso en línea:	https://doaj.org/article/710d4254d6af49999e7ddfa97af6bd63
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spelling	oai:doaj.org-article:710d4254d6af49999e7ddfa97af6bd632021-12-02T19:10:31ZCentral and peripheral control of food intake1336-032910.1515/enr-2017-0006https://doaj.org/article/710d4254d6af49999e7ddfa97af6bd632017-01-01T00:00:00Zhttps://doi.org/10.1515/enr-2017-0006https://doaj.org/toc/1336-0329The maintenance of the body weight at a stable level is a major determinant in keeping the higher animals and mammals survive. Th e body weight depends on the balance between the energy intake and energy expenditure. Increased food intake over the energy expenditure of prolonged time period results in an obesity. Th e obesity has become an important worldwide health problem, even at low levels. The obesity has an evil effect on the health and is associated with a shorter life expectancy. A complex of central and peripheral physiological signals is involved in the control of the food intake. Centrally, the food intake is controlled by the hypothalamus, the brainstem, and endocannabinoids and peripherally by the satiety and adiposity signals. Comprehension of the signals that control food intake and energy balance may open a new therapeutic approaches directed against the obesity and its associated complications, as is the insulin resistance and others. In conclusion, the present review summarizes the current knowledge about the complex system of the peripheral and central regulatory mechanisms of food intake and their potential therapeutic implications in the treatment of obesity.Abdalla M. M. I.Sciendoarticlefood intakegastrointestinal hormonesenergy balancesatiety signalsadiposity signalsDiseases of the endocrine glands. Clinical endocrinologyRC648-665ENEndocrine Regulations, Vol 51, Iss 1, Pp 52-70 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	food intake gastrointestinal hormones energy balance satiety signals adiposity signals Diseases of the endocrine glands. Clinical endocrinology RC648-665
spellingShingle	food intake gastrointestinal hormones energy balance satiety signals adiposity signals Diseases of the endocrine glands. Clinical endocrinology RC648-665 Abdalla M. M. I. Central and peripheral control of food intake
description	The maintenance of the body weight at a stable level is a major determinant in keeping the higher animals and mammals survive. Th e body weight depends on the balance between the energy intake and energy expenditure. Increased food intake over the energy expenditure of prolonged time period results in an obesity. Th e obesity has become an important worldwide health problem, even at low levels. The obesity has an evil effect on the health and is associated with a shorter life expectancy. A complex of central and peripheral physiological signals is involved in the control of the food intake. Centrally, the food intake is controlled by the hypothalamus, the brainstem, and endocannabinoids and peripherally by the satiety and adiposity signals. Comprehension of the signals that control food intake and energy balance may open a new therapeutic approaches directed against the obesity and its associated complications, as is the insulin resistance and others. In conclusion, the present review summarizes the current knowledge about the complex system of the peripheral and central regulatory mechanisms of food intake and their potential therapeutic implications in the treatment of obesity.
format	article
author	Abdalla M. M. I.
author_facet	Abdalla M. M. I.
author_sort	Abdalla M. M. I.
title	Central and peripheral control of food intake
title_short	Central and peripheral control of food intake
title_full	Central and peripheral control of food intake
title_fullStr	Central and peripheral control of food intake
title_full_unstemmed	Central and peripheral control of food intake
title_sort	central and peripheral control of food intake
publisher	Sciendo
publishDate	2017
url	https://doaj.org/article/710d4254d6af49999e7ddfa97af6bd63
work_keys_str_mv	AT abdallammi centralandperipheralcontroloffoodintake
_version_	1718377093154209792

Central and peripheral control of food intake

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