Vitamin D, Magnesium and Their Interactions: A Review

Multiple functions in our body require vitamin D and magnesium. Magnesium acts as a co-factor along with more than 600 enzymes, including enzymes that activate and inactivate vitamin D. In recent years, with the increase in consumption of processed foods, the consumption of magnesium has decreased....

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Autores principales: Zeinab Shahsavani, Amirhossein Asadi, Elahe Shamshirgardi, Marzieh Akbarzadeh
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Publicado: Shiraz University of Medical Sciences 2021
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spelling oai:doaj.org-article:710fc85a04ee424fa327f9d7210e571b2021-11-04T07:40:11ZVitamin D, Magnesium and Their Interactions: A Review2538-18732538-282910.30476/ijns.2021.91766.1144https://doaj.org/article/710fc85a04ee424fa327f9d7210e571b2021-09-01T00:00:00Zhttps://ijns.sums.ac.ir/article_47789_d57ff3f9dd0ed84f0bb26798b73516c9.pdfhttps://doaj.org/toc/2538-1873https://doaj.org/toc/2538-2829Multiple functions in our body require vitamin D and magnesium. Magnesium acts as a co-factor along with more than 600 enzymes, including enzymes that activate and inactivate vitamin D. In recent years, with the increase in consumption of processed foods, the consumption of magnesium has decreased. Magnesium defciency can be associated with abnormal vitamin D function. Magnesium acts as a co-factor in the activation and inactivation of vitamin D. In addition, magnesium is required for the binding of vitamin D to its transporter protein and the expression of vitamin D receptors for cellular effects. On the other hand, vitamin D can affect the state of magnesium in the body. In this way, activated vitamin D in turn can increase the intestinal absorption of magnesium. Dysregulation in any of these nutrients can be associated with various disorders such as skeletal abnormalities, cardiovascular disorders and metabolic syndrome. It seems that considering magnesium along with vitamin D is a good approach to improve the function of vitamin D in the body.Zeinab ShahsavaniAmirhossein AsadiElahe ShamshirgardiMarzieh AkbarzadehShiraz University of Medical Sciencesarticlevitamin dmagnesiumnutritiondefciencyNutritional diseases. Deficiency diseasesRC620-627ENInternational Journal of Nutrition Sciences, Vol 6, Iss 3, Pp 113-118 (2021)
institution DOAJ
collection DOAJ
language EN
topic vitamin d
magnesium
nutrition
defciency
Nutritional diseases. Deficiency diseases
RC620-627
spellingShingle vitamin d
magnesium
nutrition
defciency
Nutritional diseases. Deficiency diseases
RC620-627
Zeinab Shahsavani
Amirhossein Asadi
Elahe Shamshirgardi
Marzieh Akbarzadeh
Vitamin D, Magnesium and Their Interactions: A Review
description Multiple functions in our body require vitamin D and magnesium. Magnesium acts as a co-factor along with more than 600 enzymes, including enzymes that activate and inactivate vitamin D. In recent years, with the increase in consumption of processed foods, the consumption of magnesium has decreased. Magnesium defciency can be associated with abnormal vitamin D function. Magnesium acts as a co-factor in the activation and inactivation of vitamin D. In addition, magnesium is required for the binding of vitamin D to its transporter protein and the expression of vitamin D receptors for cellular effects. On the other hand, vitamin D can affect the state of magnesium in the body. In this way, activated vitamin D in turn can increase the intestinal absorption of magnesium. Dysregulation in any of these nutrients can be associated with various disorders such as skeletal abnormalities, cardiovascular disorders and metabolic syndrome. It seems that considering magnesium along with vitamin D is a good approach to improve the function of vitamin D in the body.
format article
author Zeinab Shahsavani
Amirhossein Asadi
Elahe Shamshirgardi
Marzieh Akbarzadeh
author_facet Zeinab Shahsavani
Amirhossein Asadi
Elahe Shamshirgardi
Marzieh Akbarzadeh
author_sort Zeinab Shahsavani
title Vitamin D, Magnesium and Their Interactions: A Review
title_short Vitamin D, Magnesium and Their Interactions: A Review
title_full Vitamin D, Magnesium and Their Interactions: A Review
title_fullStr Vitamin D, Magnesium and Their Interactions: A Review
title_full_unstemmed Vitamin D, Magnesium and Their Interactions: A Review
title_sort vitamin d, magnesium and their interactions: a review
publisher Shiraz University of Medical Sciences
publishDate 2021
url https://doaj.org/article/710fc85a04ee424fa327f9d7210e571b
work_keys_str_mv AT zeinabshahsavani vitamindmagnesiumandtheirinteractionsareview
AT amirhosseinasadi vitamindmagnesiumandtheirinteractionsareview
AT elaheshamshirgardi vitamindmagnesiumandtheirinteractionsareview
AT marziehakbarzadeh vitamindmagnesiumandtheirinteractionsareview
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