ROLE OF HUMORAL IMMUNE FACTORS IN ELIMINATION OF TICK-BORNE ENCEPHALITIS VIRUS IN NON-VACCINATED PERSONS, AND IN THOSE VACCINATED AGAINST TICK-BORNE ENCEPHALITIS

Abstract. We present some results concerning investigation of humoral immune factors (virus-specific antibodies, complement components, total serum immunoglobulins, circulating immune complexes), and the levels of tick-borne encephalitis (TBE) viral antigenemia in the persons subjected to stings of...

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Autores principales:	N. V. Krylova, G. N. Leonova, E. V. Pavlenko, I. G. Maksema
Formato:	article
Lenguaje:	RU
Publicado:	SPb RAACI 2014
Materias:	tick-borne encephalitis humoral immunity virus elimination Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/7127f1ae2b2449ca979612be68eb4ad2
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spelling	oai:doaj.org-article:7127f1ae2b2449ca979612be68eb4ad22021-11-18T08:03:40ZROLE OF HUMORAL IMMUNE FACTORS IN ELIMINATION OF TICK-BORNE ENCEPHALITIS VIRUS IN NON-VACCINATED PERSONS, AND IN THOSE VACCINATED AGAINST TICK-BORNE ENCEPHALITIS1563-06252313-741X10.15789/1563-0625-2009-2-3-197-204https://doaj.org/article/7127f1ae2b2449ca979612be68eb4ad22014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/293https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XAbstract. We present some results concerning investigation of humoral immune factors (virus-specific antibodies, complement components, total serum immunoglobulins, circulating immune complexes), and the levels of tick-borne encephalitis (TBE) viral antigenemia in the persons subjected to stings of ticks. Elimination of the virus in vaccinated people with short-term antigenemia, with higher indices of innate humoral immunity and virus-specific antibodies, proved to be faster while being more complete than in non-vaccinated persons. In cases of a long-term TBE antigenemia, both vaccinated and non-vaccinated people showed low levels of virusspecific antibodies along with decreased natural resistance, thus, probably, contributing to delayed elimination of TBE virus.N. V. KrylovaG. N. LeonovaE. V. PavlenkoI. G. MaksemaSPb RAACIarticletick-borne encephalitishumoral immunityvirus eliminationImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 11, Iss 2-3, Pp 197-204 (2014)
institution	DOAJ
collection	DOAJ
language	RU
topic	tick-borne encephalitis humoral immunity virus elimination Immunologic diseases. Allergy RC581-607
spellingShingle	tick-borne encephalitis humoral immunity virus elimination Immunologic diseases. Allergy RC581-607 N. V. Krylova G. N. Leonova E. V. Pavlenko I. G. Maksema ROLE OF HUMORAL IMMUNE FACTORS IN ELIMINATION OF TICK-BORNE ENCEPHALITIS VIRUS IN NON-VACCINATED PERSONS, AND IN THOSE VACCINATED AGAINST TICK-BORNE ENCEPHALITIS
description	Abstract. We present some results concerning investigation of humoral immune factors (virus-specific antibodies, complement components, total serum immunoglobulins, circulating immune complexes), and the levels of tick-borne encephalitis (TBE) viral antigenemia in the persons subjected to stings of ticks. Elimination of the virus in vaccinated people with short-term antigenemia, with higher indices of innate humoral immunity and virus-specific antibodies, proved to be faster while being more complete than in non-vaccinated persons. In cases of a long-term TBE antigenemia, both vaccinated and non-vaccinated people showed low levels of virusspecific antibodies along with decreased natural resistance, thus, probably, contributing to delayed elimination of TBE virus.
format	article
author	N. V. Krylova G. N. Leonova E. V. Pavlenko I. G. Maksema
author_facet	N. V. Krylova G. N. Leonova E. V. Pavlenko I. G. Maksema
author_sort	N. V. Krylova
title	ROLE OF HUMORAL IMMUNE FACTORS IN ELIMINATION OF TICK-BORNE ENCEPHALITIS VIRUS IN NON-VACCINATED PERSONS, AND IN THOSE VACCINATED AGAINST TICK-BORNE ENCEPHALITIS
title_short	ROLE OF HUMORAL IMMUNE FACTORS IN ELIMINATION OF TICK-BORNE ENCEPHALITIS VIRUS IN NON-VACCINATED PERSONS, AND IN THOSE VACCINATED AGAINST TICK-BORNE ENCEPHALITIS
title_full	ROLE OF HUMORAL IMMUNE FACTORS IN ELIMINATION OF TICK-BORNE ENCEPHALITIS VIRUS IN NON-VACCINATED PERSONS, AND IN THOSE VACCINATED AGAINST TICK-BORNE ENCEPHALITIS
title_fullStr	ROLE OF HUMORAL IMMUNE FACTORS IN ELIMINATION OF TICK-BORNE ENCEPHALITIS VIRUS IN NON-VACCINATED PERSONS, AND IN THOSE VACCINATED AGAINST TICK-BORNE ENCEPHALITIS
title_full_unstemmed	ROLE OF HUMORAL IMMUNE FACTORS IN ELIMINATION OF TICK-BORNE ENCEPHALITIS VIRUS IN NON-VACCINATED PERSONS, AND IN THOSE VACCINATED AGAINST TICK-BORNE ENCEPHALITIS
title_sort	role of humoral immune factors in elimination of tick-borne encephalitis virus in non-vaccinated persons, and in those vaccinated against tick-borne encephalitis
publisher	SPb RAACI
publishDate	2014
url	https://doaj.org/article/7127f1ae2b2449ca979612be68eb4ad2
work_keys_str_mv	AT nvkrylova roleofhumoralimmunefactorsineliminationoftickborneencephalitisvirusinnonvaccinatedpersonsandinthosevaccinatedagainsttickborneencephalitis AT gnleonova roleofhumoralimmunefactorsineliminationoftickborneencephalitisvirusinnonvaccinatedpersonsandinthosevaccinatedagainsttickborneencephalitis AT evpavlenko roleofhumoralimmunefactorsineliminationoftickborneencephalitisvirusinnonvaccinatedpersonsandinthosevaccinatedagainsttickborneencephalitis AT igmaksema roleofhumoralimmunefactorsineliminationoftickborneencephalitisvirusinnonvaccinatedpersonsandinthosevaccinatedagainsttickborneencephalitis
_version_	1718422483306020864

ROLE OF HUMORAL IMMUNE FACTORS IN ELIMINATION OF TICK-BORNE ENCEPHALITIS VIRUS IN NON-VACCINATED PERSONS, AND IN THOSE VACCINATED AGAINST TICK-BORNE ENCEPHALITIS

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