Dynamic methylation of histone H3K18 in differentiating Theileria parasites

Post-translational modifications (PTM) of histones are important for epigenetic regulation in mammals. Here, Cheeseman et al. report dynamic changes in H3K18 PTM during the differentiation stages of Theileria parasites and they identify a SET-domain methyltransferase (TaSETup1) as the relevant enzym...

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Autores principales: Kevin Cheeseman, Guillaume Jannot, Nelly Lourenço, Marie Villares, Jérémy Berthelet, Teresa Calegari-Silva, Juliette Hamroune, Franck Letourneur, Fernando Rodrigues-Lima, Jonathan B. Weitzman
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Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/712fda1c16454d07921464f027030122
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spelling oai:doaj.org-article:712fda1c16454d07921464f0270301222021-12-02T15:49:44ZDynamic methylation of histone H3K18 in differentiating Theileria parasites10.1038/s41467-021-23477-22041-1723https://doaj.org/article/712fda1c16454d07921464f0270301222021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23477-2https://doaj.org/toc/2041-1723Post-translational modifications (PTM) of histones are important for epigenetic regulation in mammals. Here, Cheeseman et al. report dynamic changes in H3K18 PTM during the differentiation stages of Theileria parasites and they identify a SET-domain methyltransferase (TaSETup1) as the relevant enzyme promoting this modification.Kevin CheesemanGuillaume JannotNelly LourençoMarie VillaresJérémy BertheletTeresa Calegari-SilvaJuliette HamrouneFranck LetourneurFernando Rodrigues-LimaJonathan B. WeitzmanNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Kevin Cheeseman
Guillaume Jannot
Nelly Lourenço
Marie Villares
Jérémy Berthelet
Teresa Calegari-Silva
Juliette Hamroune
Franck Letourneur
Fernando Rodrigues-Lima
Jonathan B. Weitzman
Dynamic methylation of histone H3K18 in differentiating Theileria parasites
description Post-translational modifications (PTM) of histones are important for epigenetic regulation in mammals. Here, Cheeseman et al. report dynamic changes in H3K18 PTM during the differentiation stages of Theileria parasites and they identify a SET-domain methyltransferase (TaSETup1) as the relevant enzyme promoting this modification.
format article
author Kevin Cheeseman
Guillaume Jannot
Nelly Lourenço
Marie Villares
Jérémy Berthelet
Teresa Calegari-Silva
Juliette Hamroune
Franck Letourneur
Fernando Rodrigues-Lima
Jonathan B. Weitzman
author_facet Kevin Cheeseman
Guillaume Jannot
Nelly Lourenço
Marie Villares
Jérémy Berthelet
Teresa Calegari-Silva
Juliette Hamroune
Franck Letourneur
Fernando Rodrigues-Lima
Jonathan B. Weitzman
author_sort Kevin Cheeseman
title Dynamic methylation of histone H3K18 in differentiating Theileria parasites
title_short Dynamic methylation of histone H3K18 in differentiating Theileria parasites
title_full Dynamic methylation of histone H3K18 in differentiating Theileria parasites
title_fullStr Dynamic methylation of histone H3K18 in differentiating Theileria parasites
title_full_unstemmed Dynamic methylation of histone H3K18 in differentiating Theileria parasites
title_sort dynamic methylation of histone h3k18 in differentiating theileria parasites
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/712fda1c16454d07921464f027030122
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AT marievillares dynamicmethylationofhistoneh3k18indifferentiatingtheileriaparasites
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