Biodegradable thermosensitive hydrogel for SAHA and DDP delivery: therapeutic effects on oral squamous cell carcinoma xenografts.

Biodegradable thermosensitive hydrogel for SAHA and DDP delivery: therapeutic effects on oral squamous cell carcinoma xenografts.

<h4>Background</h4>OSCC is one of the most common malignancies and numerous clinical agents currently applied in combinative chemotherapy. Here we reported a novel therapeutic strategy, SAHA and DDP-loaded PECE (SAHA-DDP/PECE), can improve the therapeutic effects of intratumorally chemot...

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Autores principales: Jing Li, Changyang Gong, Xiaodong Feng, Xikun Zhou, Xiaoping Xu, Liang Xie, Ruinan Wang, Dunfang Zhang, Hui Wang, Peng Deng, Min Zhou, Ning Ji, Yu Zhou, Yun Wang, Zhiyong Wang, Ga Liao, Ning Geng, Liangyin Chu, Zhiyong Qian, Zhi Wang, Qianming Chen
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/71301349b8af4b8fad62443dbb9413fc
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