Overexpression of MAP3K3 promotes tumour growth through activation of the NF-κB signalling pathway in ovarian carcinoma

Código QR

Overexpression of MAP3K3 promotes tumour growth through activation of the NF-κB signalling pathway in ovarian carcinoma

Abstract Mitogen-activated protein kinase kinase kinase 3 (MAP3K3), a member of the serine/threonine protein kinase family, is ubiquitously expressed and acts as an oncogene. However, the expression and exact molecular mechanism of MAP3K3 in ovarian carcinoma (OC) remain unclear. Here, we found that...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Ying Zhang, Sha-Sha Wang, Lin Tao, Li-Juan Pang, Hong Zou, Wei-Hua Liang, Zheng Liu, Su-Liang Guo, Jin-Fang Jiang, Wen-Jie Zhang, Wei Jia, Feng Li
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/71306ad817304110b9d1b3ce0fd7f3ed
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

Chang-wei-qing, a Chinese herbal formula, ameliorates colitis-associated tumour development via inhibiting NF-κB and STAT3 signalling pathway
por: Guangsheng Wan, et al.
Publicado: (2019)

MKL1 defines the H3K4Me3 landscape for NF-κB dependent inflammatory response
por: Liming Yu, et al.
Publicado: (2017)

Eupafolin induces apoptosis and autophagy of breast cancer cells through PI3K/AKT, MAPKs and NF-κB signaling pathways
por: Jiahui Wei, et al.
Publicado: (2021)

CircSETDB1 knockdown inhibits the malignant progression of serous ovarian cancer through miR-129-3p-dependent regulation of MAP3K3
por: Bo Li, et al.
Publicado: (2021)

LFG-500 inhibits the invasion of cancer cells via down-regulation of PI3K/AKT/NF-κB signaling pathway.
por: Chenglin Li, et al.
Publicado: (2014)

A20 (TNFAIP3) alleviates CVB3-induced myocarditis via inhibiting NF-κB signaling.
por: Jun Gui, et al.
Publicado: (2012)

Luteolin Improves Cyclophosphamide-Induced Cystitis through TXNIP/NLRP3 and NF-κB Pathways
por: Hengshuai Zhang, et al.
Publicado: (2021)

Overexpression of PIK3R1 promotes hepatocellular carcinoma progression
por: Ai,Xuejun, et al.
Publicado: (2018)

Baicalin ameliorates APEC-induced intestinal injury in chicks by inhibiting the PI3K/AKT-mediated NF-κB signaling pathway
por: Xinyi Cheng, et al.
Publicado: (2022)

IPA-3 inhibits the growth of liver cancer cells by suppressing PAK1 and NF-κB activation.
por: Leo Lap-Yan Wong, et al.
Publicado: (2013)

Neuroprotective effect of kaempferol glycosides against brain injury and neuroinflammation by inhibiting the activation of NF-κB and STAT3 in transient focal stroke.
por: Lu Yu, et al.
Publicado: (2013)

Genomic locus proteomic screening identifies the NF-κB signaling pathway components NFκB1 and IKBKG as transcriptional regulators of Ripk3 in endothelial cells.
por: Siqi Gao, et al.
Publicado: (2021)

Expression Of Intracellular Components of the NF-κB Alternative Pathway (NF-κB2, RelB, NIK and Bcl3) is Associated With Clinical Outcome of NSCLC Patients
por: Foteinos-Ioannis D. Dimitrakopoulos, et al.
Publicado: (2019)

Metformin Corrects Glucose Metabolism Reprogramming and NLRP3 Inflammasome-Induced Pyroptosis via Inhibiting the TLR4/NF-κB/PFKFB3 Signaling in Trophoblasts: Implication for a Potential Therapy of Preeclampsia
por: Yang Zhang, et al.
Publicado: (2021)

PAR1 and PAR4 exert opposite effects on tumor growth and metastasis of esophageal squamous cell carcinoma via STAT3 and NF-κB signaling pathways
por: Jia Zhao, et al.
Publicado: (2021)

TSPAN15 interacts with BTRC to promote oesophageal squamous cell carcinoma metastasis via activating NF-κB signaling
por: Baozhu Zhang, et al.
Publicado: (2018)

Multiple genetic alterations within the PI3K pathway are responsible for AKT activation in patients with ovarian carcinoma.
por: Carmela De Marco, et al.
Publicado: (2013)

Tumour-specific PI3K inhibition via nanoparticle-targeted delivery in head and neck squamous cell carcinoma
por: Aviram Mizrachi, et al.
Publicado: (2017)

The REGγ-proteasome forms a regulatory circuit with IκBɛ and NFκB in experimental colitis
por: Jinjin Xu, et al.
Publicado: (2016)

Inhibition of specific NF-κB activity contributes to the tumor suppressor function of 14-3-3σ in breast cancer.
por: Julia Inglés-Esteve, et al.
Publicado: (2012)

Nipah virus W protein harnesses nuclear 14-3-3 to inhibit NF-κB-induced proinflammatory response
por: François Enchéry, et al.
Publicado: (2021)

Regulation of NF-κB activation through a novel PI-3K-independent and PKA/Akt-dependent pathway in human umbilical vein endothelial cells.
por: Sakshi Balwani, et al.
Publicado: (2012)

Acupuncture regulates the autophagy of ovarian granulosa cells in polycystic ovarian syndrome ovulation disorder by inhibiting the PI3K/AKT/mTOR pathway through LncMEG3
por: Xiaohong Chen, et al.
Publicado: (2021)

REV-ERBα integrates colon clock with experimental colitis through regulation of NF-κB/NLRP3 axis
por: Shuai Wang, et al.
Publicado: (2018)

MYD88 signals induce tumour-initiating cell generation through the NF-κB-HIF-1α activation cascade
por: Atsuko Tanimura, et al.
Publicado: (2021)

ω-3 DPA Protected Neurons from Neuroinflammation by Balancing Microglia M1/M2 Polarizations through Inhibiting NF-κB/MAPK p38 Signaling and Activating Neuron-BDNF-PI3K/AKT Pathways
por: Baiping Liu, et al.
Publicado: (2021)

Author Correction: Wogonin reversed resistant human myelogenous leukemia cells via inhibiting Nrf2 signaling by Stat3/ NF-κB inactivation
por: Xuefen Xu, et al.
Publicado: (2021)

Dexmedetomidine inhibits the NF-κB pathway and NLRP3 inflammasome to attenuate papain-induced osteoarthritis in rats
por: Fang Cheng, et al.
Publicado: (2019)

SLCO3A1, A novel crohn's disease-associated gene, regulates nf-κB activity and associates with intestinal perforation.
por: Shu-Chen Wei, et al.
Publicado: (2014)

AATF is Overexpressed in Human Head and Neck Squamous Cell Carcinoma and Regulates STAT3/Survivin Signaling
por: Fu L, et al.
Publicado: (2021)

Dauricine Attenuates Vascular Endothelial Inflammation Through Inhibiting NF-κB Pathway
por: Ji Hu, et al.
Publicado: (2021)

L-arabinose alleviates diabetes-aggravated cerebral ischemic injury by repairing the blood-brain barrier via downregulating NF-κB signals
por: Haiyan Li, et al.
Publicado: (2021)

Physalin A Inhibits MAPK and NF-κB Signal Transduction Through Integrin αVβ3 and Exerts Chondroprotective Effect
por: Rui Lu, et al.
Publicado: (2021)

Artesunate attenuates inflammatory injury and inhibits the NF-κB pathway in a mouse model of cerebral ischemia
por: Ying Liu, et al.
Publicado: (2021)

GRAMD4 inhibits tumour metastasis by recruiting the E3 ligase ITCH to target TAK1 for degradation in hepatocellular carcinoma
por: Qian yun Ge, et al.
Publicado: (2021)

SENP7 knockdown inhibited pyroptosis and NF-κB/NLRP3 inflammasome pathway activation in Raw 264.7 cells
por: Xun Li, et al.
Publicado: (2020)

MKL1 regulates hepatocellular carcinoma cell proliferation, migration and apoptosis via the COMPASS complex and NF-κB signaling
por: Zhao Liu, et al.
Publicado: (2021)

The MIRNA mir-582-3p suppresses ovarian cancer progression by targeting AKT/MTOR signaling via lncRNA TUG1
por: Tianyu Dai, et al.
Publicado: (2021)

Moxibustion Inhibits the Expression of Colonic NLRP3 through miR7/RNF183/NF-κB Signaling Pathway in UC Rats
por: Xi-Ying Li, et al.
Publicado: (2021)

Nrf3 Promotes 5-FU Resistance in Colorectal Cancer Cells via the NF-κB/BCL-2 Signaling Pathway In Vitro and In Vivo
por: Bi-Qing Cai, et al.
Publicado: (2021)