Effect of glucose deprivation on the expression of genes encoding glucocorticoid receptor and some related factors in ERN1-knockdown U87 glioma cells

Objective. The aim of the present study was to examine the effect of glucose deprivation on the expression of genes encoded glucocorticoid receptor (NR3C1) and some related proteins (NR3C2, AHR, NRIP1, NNT, ARHGAP35, SGK1, and SGK3) in U87 glioma cells in response to inhibition of endoplasmic reticu...

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Autores principales: Riabovol Olena O., Tsymbal Dariia O., Minchenko Dmytro O., Lebid-Biletska Kateryna M., Sliusar Myroslava Y., Rudnytska Olha V., Minchenko Oleksandr H.
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Lenguaje:EN
Publicado: Sciendo 2019
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Acceso en línea:https://doaj.org/article/71331b31d511415d98ac7a7bd842412a
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spelling oai:doaj.org-article:71331b31d511415d98ac7a7bd842412a2021-12-02T17:49:32ZEffect of glucose deprivation on the expression of genes encoding glucocorticoid receptor and some related factors in ERN1-knockdown U87 glioma cells1336-032910.2478/enr-2019-0024https://doaj.org/article/71331b31d511415d98ac7a7bd842412a2019-10-01T00:00:00Zhttps://doi.org/10.2478/enr-2019-0024https://doaj.org/toc/1336-0329Objective. The aim of the present study was to examine the effect of glucose deprivation on the expression of genes encoded glucocorticoid receptor (NR3C1) and some related proteins (NR3C2, AHR, NRIP1, NNT, ARHGAP35, SGK1, and SGK3) in U87 glioma cells in response to inhibition of endoplasmic reticulum stress signaling mediated by ERN1/IRE1 (endoplasmic reticulum to nucleus signaling 1/inositol requiring enzyme 1) for evaluation of their possible significance in the control of glioma growth through endoplasmic reticulum stress signaling mediated by IRE1 and glucose deprivation.Riabovol Olena O.Tsymbal Dariia O.Minchenko Dmytro O.Lebid-Biletska Kateryna M.Sliusar Myroslava Y.Rudnytska Olha V.Minchenko Oleksandr H.Sciendoarticleglucose deprivationmrna expressionnr3c1nr3c2ahrnrip1sgk1sgk3arhgap35nntern1 inhibitionu87 glioma cellsDiseases of the endocrine glands. Clinical endocrinologyRC648-665ENEndocrine Regulations, Vol 53, Iss 4, Pp 237-249 (2019)
institution DOAJ
collection DOAJ
language EN
topic glucose deprivation
mrna expression
nr3c1
nr3c2
ahr
nrip1
sgk1
sgk3
arhgap35
nnt
ern1 inhibition
u87 glioma cells
Diseases of the endocrine glands. Clinical endocrinology
RC648-665
spellingShingle glucose deprivation
mrna expression
nr3c1
nr3c2
ahr
nrip1
sgk1
sgk3
arhgap35
nnt
ern1 inhibition
u87 glioma cells
Diseases of the endocrine glands. Clinical endocrinology
RC648-665
Riabovol Olena O.
Tsymbal Dariia O.
Minchenko Dmytro O.
Lebid-Biletska Kateryna M.
Sliusar Myroslava Y.
Rudnytska Olha V.
Minchenko Oleksandr H.
Effect of glucose deprivation on the expression of genes encoding glucocorticoid receptor and some related factors in ERN1-knockdown U87 glioma cells
description Objective. The aim of the present study was to examine the effect of glucose deprivation on the expression of genes encoded glucocorticoid receptor (NR3C1) and some related proteins (NR3C2, AHR, NRIP1, NNT, ARHGAP35, SGK1, and SGK3) in U87 glioma cells in response to inhibition of endoplasmic reticulum stress signaling mediated by ERN1/IRE1 (endoplasmic reticulum to nucleus signaling 1/inositol requiring enzyme 1) for evaluation of their possible significance in the control of glioma growth through endoplasmic reticulum stress signaling mediated by IRE1 and glucose deprivation.
format article
author Riabovol Olena O.
Tsymbal Dariia O.
Minchenko Dmytro O.
Lebid-Biletska Kateryna M.
Sliusar Myroslava Y.
Rudnytska Olha V.
Minchenko Oleksandr H.
author_facet Riabovol Olena O.
Tsymbal Dariia O.
Minchenko Dmytro O.
Lebid-Biletska Kateryna M.
Sliusar Myroslava Y.
Rudnytska Olha V.
Minchenko Oleksandr H.
author_sort Riabovol Olena O.
title Effect of glucose deprivation on the expression of genes encoding glucocorticoid receptor and some related factors in ERN1-knockdown U87 glioma cells
title_short Effect of glucose deprivation on the expression of genes encoding glucocorticoid receptor and some related factors in ERN1-knockdown U87 glioma cells
title_full Effect of glucose deprivation on the expression of genes encoding glucocorticoid receptor and some related factors in ERN1-knockdown U87 glioma cells
title_fullStr Effect of glucose deprivation on the expression of genes encoding glucocorticoid receptor and some related factors in ERN1-knockdown U87 glioma cells
title_full_unstemmed Effect of glucose deprivation on the expression of genes encoding glucocorticoid receptor and some related factors in ERN1-knockdown U87 glioma cells
title_sort effect of glucose deprivation on the expression of genes encoding glucocorticoid receptor and some related factors in ern1-knockdown u87 glioma cells
publisher Sciendo
publishDate 2019
url https://doaj.org/article/71331b31d511415d98ac7a7bd842412a
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