Antimicrobial peptides in frog poisons constitute a molecular toxin delivery system against predators

To avoid being eaten, poisonous prey animals must rely on fast passage of toxins across a predator’s oral tissue, a major barrier to large molecules. Here, Raaymakers et al. show that antimicrobial peptides co secreted with frog toxins enhance intoxication of a snake predator by permeabilizing oral...

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Autores principales:	Constantijn Raaymakers, Elin Verbrugghe, Sophie Hernot, Tom Hellebuyck, Cecilia Betti, Cindy Peleman, Myriam Claeys, Wim Bert, Vicky Caveliers, Steven Ballet, An Martel, Frank Pasmans, Kim Roelants
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/71406291176f47ba9bab737724a02083
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spelling	oai:doaj.org-article:71406291176f47ba9bab737724a020832021-12-02T13:24:15ZAntimicrobial peptides in frog poisons constitute a molecular toxin delivery system against predators10.1038/s41467-017-01710-12041-1723https://doaj.org/article/71406291176f47ba9bab737724a020832017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01710-1https://doaj.org/toc/2041-1723To avoid being eaten, poisonous prey animals must rely on fast passage of toxins across a predator’s oral tissue, a major barrier to large molecules. Here, Raaymakers et al. show that antimicrobial peptides co secreted with frog toxins enhance intoxication of a snake predator by permeabilizing oral cell layers.Constantijn RaaymakersElin VerbruggheSophie HernotTom HellebuyckCecilia BettiCindy PelemanMyriam ClaeysWim BertVicky CaveliersSteven BalletAn MartelFrank PasmansKim RoelantsNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-8 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Constantijn Raaymakers Elin Verbrugghe Sophie Hernot Tom Hellebuyck Cecilia Betti Cindy Peleman Myriam Claeys Wim Bert Vicky Caveliers Steven Ballet An Martel Frank Pasmans Kim Roelants Antimicrobial peptides in frog poisons constitute a molecular toxin delivery system against predators
description	To avoid being eaten, poisonous prey animals must rely on fast passage of toxins across a predator’s oral tissue, a major barrier to large molecules. Here, Raaymakers et al. show that antimicrobial peptides co secreted with frog toxins enhance intoxication of a snake predator by permeabilizing oral cell layers.
format	article
author	Constantijn Raaymakers Elin Verbrugghe Sophie Hernot Tom Hellebuyck Cecilia Betti Cindy Peleman Myriam Claeys Wim Bert Vicky Caveliers Steven Ballet An Martel Frank Pasmans Kim Roelants
author_facet	Constantijn Raaymakers Elin Verbrugghe Sophie Hernot Tom Hellebuyck Cecilia Betti Cindy Peleman Myriam Claeys Wim Bert Vicky Caveliers Steven Ballet An Martel Frank Pasmans Kim Roelants
author_sort	Constantijn Raaymakers
title	Antimicrobial peptides in frog poisons constitute a molecular toxin delivery system against predators
title_short	Antimicrobial peptides in frog poisons constitute a molecular toxin delivery system against predators
title_full	Antimicrobial peptides in frog poisons constitute a molecular toxin delivery system against predators
title_fullStr	Antimicrobial peptides in frog poisons constitute a molecular toxin delivery system against predators
title_full_unstemmed	Antimicrobial peptides in frog poisons constitute a molecular toxin delivery system against predators
title_sort	antimicrobial peptides in frog poisons constitute a molecular toxin delivery system against predators
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/71406291176f47ba9bab737724a02083
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Antimicrobial peptides in frog poisons constitute a molecular toxin delivery system against predators

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