Morphological Characteristics of Three Classic Forms of Natural Equine Glanders – A Disease With High Zoonotic Significance

Equine glanders is a severe bacterial disease known since ancient times. Although eradicated in the most part of the world it is now considered re-emerging. Considering very scarce literature data, we used from formalin fixed collection material: nasal septum, lung and skin specimens from naturally...

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Autores principales:	Aničić Milan, Kukolj Vladimir, Marinković Darko
Formato:	article
Lenguaje:	EN
Publicado:	Sciendo 2017
Materias:	glanders equine gross microscopic changes Veterinary medicine SF600-1100
Acceso en línea:	https://doaj.org/article/71456dceb2b2410883e957ea5171fb1e
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spelling	oai:doaj.org-article:71456dceb2b2410883e957ea5171fb1e2021-11-17T21:27:52ZMorphological Characteristics of Three Classic Forms of Natural Equine Glanders – A Disease With High Zoonotic Significance1820-744810.1515/acve-2017-0045https://doaj.org/article/71456dceb2b2410883e957ea5171fb1e2017-12-01T00:00:00Zhttps://doi.org/10.1515/acve-2017-0045https://doaj.org/toc/1820-7448Equine glanders is a severe bacterial disease known since ancient times. Although eradicated in the most part of the world it is now considered re-emerging. Considering very scarce literature data, we used from formalin fixed collection material: nasal septum, lung and skin specimens from naturally infected horses. Tissues were grossly examined and photographed. Tissue samples, after standard processing, were stained with HE, Congo red and Groccot and microscopically examined. Gross changes include nodules and ulcers in the nasal mucosa with granulation and scarring, pyogranulomas in the lung tissue and nodules and ulcers of the skin. Microscopically marked inflammation of affected tissues with neutrophilic and mononuclear infiltration and fibrous tissue proliferation were seen. As a potent zoonotic agent it has been already used as a biological weapon in the past.Aničić MilanKukolj VladimirMarinković DarkoSciendoarticleglandersequinegrossmicroscopic changesVeterinary medicineSF600-1100ENActa Veterinaria, Vol 67, Iss 4, Pp 572-577 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	glanders equine gross microscopic changes Veterinary medicine SF600-1100
spellingShingle	glanders equine gross microscopic changes Veterinary medicine SF600-1100 Aničić Milan Kukolj Vladimir Marinković Darko Morphological Characteristics of Three Classic Forms of Natural Equine Glanders – A Disease With High Zoonotic Significance
description	Equine glanders is a severe bacterial disease known since ancient times. Although eradicated in the most part of the world it is now considered re-emerging. Considering very scarce literature data, we used from formalin fixed collection material: nasal septum, lung and skin specimens from naturally infected horses. Tissues were grossly examined and photographed. Tissue samples, after standard processing, were stained with HE, Congo red and Groccot and microscopically examined. Gross changes include nodules and ulcers in the nasal mucosa with granulation and scarring, pyogranulomas in the lung tissue and nodules and ulcers of the skin. Microscopically marked inflammation of affected tissues with neutrophilic and mononuclear infiltration and fibrous tissue proliferation were seen. As a potent zoonotic agent it has been already used as a biological weapon in the past.
format	article
author	Aničić Milan Kukolj Vladimir Marinković Darko
author_facet	Aničić Milan Kukolj Vladimir Marinković Darko
author_sort	Aničić Milan
title	Morphological Characteristics of Three Classic Forms of Natural Equine Glanders – A Disease With High Zoonotic Significance
title_short	Morphological Characteristics of Three Classic Forms of Natural Equine Glanders – A Disease With High Zoonotic Significance
title_full	Morphological Characteristics of Three Classic Forms of Natural Equine Glanders – A Disease With High Zoonotic Significance
title_fullStr	Morphological Characteristics of Three Classic Forms of Natural Equine Glanders – A Disease With High Zoonotic Significance
title_full_unstemmed	Morphological Characteristics of Three Classic Forms of Natural Equine Glanders – A Disease With High Zoonotic Significance
title_sort	morphological characteristics of three classic forms of natural equine glanders – a disease with high zoonotic significance
publisher	Sciendo
publishDate	2017
url	https://doaj.org/article/71456dceb2b2410883e957ea5171fb1e
work_keys_str_mv	AT anicicmilan morphologicalcharacteristicsofthreeclassicformsofnaturalequineglandersadiseasewithhighzoonoticsignificance AT kukoljvladimir morphologicalcharacteristicsofthreeclassicformsofnaturalequineglandersadiseasewithhighzoonoticsignificance AT marinkovicdarko morphologicalcharacteristicsofthreeclassicformsofnaturalequineglandersadiseasewithhighzoonoticsignificance
_version_	1718425290152083456

Morphological Characteristics of Three Classic Forms of Natural Equine Glanders – A Disease With High Zoonotic Significance

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