Sensing the allosteric force

Sensing the allosteric force

Almost all allosteric systems are large multi-domain proteins which complicates the investigation of the mechanism in atomistic detail. Here authors designed a small allosteric protein system using the photocontrollable PDZ3 domain, that allows controlling allostery between the binding and allosteri...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Olga Bozovic, Brankica Jankovic, Peter Hamm
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/714b6c49fb4441989f40a38ee79d3f9c
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:714b6c49fb4441989f40a38ee79d3f9c
record_format dspace
spelling oai:doaj.org-article:714b6c49fb4441989f40a38ee79d3f9c2021-12-02T15:39:19ZSensing the allosteric force10.1038/s41467-020-19689-72041-1723https://doaj.org/article/714b6c49fb4441989f40a38ee79d3f9c2020-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19689-7https://doaj.org/toc/2041-1723Almost all allosteric systems are large multi-domain proteins which complicates the investigation of the mechanism in atomistic detail. Here authors designed a small allosteric protein system using the photocontrollable PDZ3 domain, that allows controlling allostery between the binding and allosteric site in both directions.Olga BozovicBrankica JankovicPeter HammNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-7 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Olga Bozovic
Brankica Jankovic
Peter Hamm
Sensing the allosteric force
description Almost all allosteric systems are large multi-domain proteins which complicates the investigation of the mechanism in atomistic detail. Here authors designed a small allosteric protein system using the photocontrollable PDZ3 domain, that allows controlling allostery between the binding and allosteric site in both directions.
format article
author Olga Bozovic
Brankica Jankovic
Peter Hamm
author_facet Olga Bozovic
Brankica Jankovic
Peter Hamm
author_sort Olga Bozovic
title Sensing the allosteric force
title_short Sensing the allosteric force
title_full Sensing the allosteric force
title_fullStr Sensing the allosteric force
title_full_unstemmed Sensing the allosteric force
title_sort sensing the allosteric force
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/714b6c49fb4441989f40a38ee79d3f9c
work_keys_str_mv AT olgabozovic sensingtheallostericforce
AT brankicajankovic sensingtheallostericforce
AT peterhamm sensingtheallostericforce
_version_ 1718385940160839680

Ejemplares similares