MuSyC is a consensus framework that unifies multi-drug synergy metrics for combinatorial drug discovery

The lack of a unifying metric characterizing combinatorial drug interactions has impeded the development of combinatorial therapies. Here, the authors present MuSyC, a consensus synergy metric that overcomes several caveats associated with other, popular metrics.

Guardado en:
Detalles Bibliográficos
Autores principales: David J. Wooten, Christian T. Meyer, Alexander L. R. Lubbock, Vito Quaranta, Carlos F. Lopez
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Q
Acceso en línea:https://doaj.org/article/714bcb94521f45b18fccb436c738bfea
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
Descripción
Sumario:The lack of a unifying metric characterizing combinatorial drug interactions has impeded the development of combinatorial therapies. Here, the authors present MuSyC, a consensus synergy metric that overcomes several caveats associated with other, popular metrics.