MuSyC is a consensus framework that unifies multi-drug synergy metrics for combinatorial drug discovery

The lack of a unifying metric characterizing combinatorial drug interactions has impeded the development of combinatorial therapies. Here, the authors present MuSyC, a consensus synergy metric that overcomes several caveats associated with other, popular metrics.

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Autores principales:	David J. Wooten, Christian T. Meyer, Alexander L. R. Lubbock, Vito Quaranta, Carlos F. Lopez
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/714bcb94521f45b18fccb436c738bfea
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spelling	oai:doaj.org-article:714bcb94521f45b18fccb436c738bfea2021-12-02T18:47:04ZMuSyC is a consensus framework that unifies multi-drug synergy metrics for combinatorial drug discovery10.1038/s41467-021-24789-z2041-1723https://doaj.org/article/714bcb94521f45b18fccb436c738bfea2021-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24789-zhttps://doaj.org/toc/2041-1723The lack of a unifying metric characterizing combinatorial drug interactions has impeded the development of combinatorial therapies. Here, the authors present MuSyC, a consensus synergy metric that overcomes several caveats associated with other, popular metrics.David J. WootenChristian T. MeyerAlexander L. R. LubbockVito QuarantaCarlos F. LopezNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q David J. Wooten Christian T. Meyer Alexander L. R. Lubbock Vito Quaranta Carlos F. Lopez MuSyC is a consensus framework that unifies multi-drug synergy metrics for combinatorial drug discovery
description	The lack of a unifying metric characterizing combinatorial drug interactions has impeded the development of combinatorial therapies. Here, the authors present MuSyC, a consensus synergy metric that overcomes several caveats associated with other, popular metrics.
format	article
author	David J. Wooten Christian T. Meyer Alexander L. R. Lubbock Vito Quaranta Carlos F. Lopez
author_facet	David J. Wooten Christian T. Meyer Alexander L. R. Lubbock Vito Quaranta Carlos F. Lopez
author_sort	David J. Wooten
title	MuSyC is a consensus framework that unifies multi-drug synergy metrics for combinatorial drug discovery
title_short	MuSyC is a consensus framework that unifies multi-drug synergy metrics for combinatorial drug discovery
title_full	MuSyC is a consensus framework that unifies multi-drug synergy metrics for combinatorial drug discovery
title_fullStr	MuSyC is a consensus framework that unifies multi-drug synergy metrics for combinatorial drug discovery
title_full_unstemmed	MuSyC is a consensus framework that unifies multi-drug synergy metrics for combinatorial drug discovery
title_sort	musyc is a consensus framework that unifies multi-drug synergy metrics for combinatorial drug discovery
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/714bcb94521f45b18fccb436c738bfea
work_keys_str_mv	AT davidjwooten musycisaconsensusframeworkthatunifiesmultidrugsynergymetricsforcombinatorialdrugdiscovery AT christiantmeyer musycisaconsensusframeworkthatunifiesmultidrugsynergymetricsforcombinatorialdrugdiscovery AT alexanderlrlubbock musycisaconsensusframeworkthatunifiesmultidrugsynergymetricsforcombinatorialdrugdiscovery AT vitoquaranta musycisaconsensusframeworkthatunifiesmultidrugsynergymetricsforcombinatorialdrugdiscovery AT carlosflopez musycisaconsensusframeworkthatunifiesmultidrugsynergymetricsforcombinatorialdrugdiscovery
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MuSyC is a consensus framework that unifies multi-drug synergy metrics for combinatorial drug discovery

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